Physician's Weekly

JUNE 18, 2025

WEDNESDAY, June 18, 2025 (HealthDay News) — For patients with schizophrenia, weekly LYN-005 provides sustained release of risperidone at therapeutic concentrations, according to a study published online June 11 in The Lancet Psychiatry. Eighty-three patients were enrolled in the study, 47 of whom completed the study.

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Physician's Weekly

JUNE 24, 2025

Biomarkers were measured in stored plasma and urine collected five months after enrollment, and a regression tree-based model was constructed using a panel of clinically relevant biomarkers to predict the time to the composite event. A total of 599 children were included; 205 (34 percent) reached the primary outcome of CKD progression.

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Utilities Clinic Individual Patients 52

Annals of Family Medicine

NOVEMBER 20, 2024

Context: Clinicians and patients often face a decision to continue or discontinue statins to maximize benefit and minimize the risk of harm. Population Studied: Adults ≥18 years Intervention/Instrument: Discontinuation of statin medications Outcome Measures: All-cause mortality, cardiovascular (CV) mortality, and CV events (e.g.,

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My Green Doctor

APRIL 4, 2025

In This Issue : New Research: Teaching Patients about Climate Resilience Make the Pledge Today to Go Green Get Ready for Earth Day 2025 (part 2)! According to the 2023 report of the Lancet Countdown, mortality caused by extreme heat events increased by 53.7% from 2000 to 2018 among people over 65 years old. Contact us today!

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Annals of Family Medicine

NOVEMBER 20, 2024

Context Ten percent of patients using prescription drugs experience adverse drug events (ADE). A proportion of these ADEs can be explained by a difference in enzyme activity between individuals. Intra-individual variation in genetic composition is one of the key contributing factors determining enzyme activity.

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Physician's Weekly

JUNE 14, 2025

Grade ≥3 treatment-related adverse events (AEs) occurred in 192 of 615 (31.2%) participants receiving at least 1 dose of pembrolizumab plus enzalutamide and in 67 of 620 (10.8%) receiving at least 1 dose of placebo plus enzalutamide. Prior use of abiraterone was allowed. months (hazard ratio [HR], 1.04 [95% CI, 0.88–1.22];

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Individual Patients 52

Physician's Weekly

JUNE 11, 2025

First, to meet protein needs, patients can be counseled to include 30 grams of high-quality protein sources at each meal. I envision primary care clinicians playing an important role in assessing the individual needs of the older adult patient and helping them access essential elements of the care plan.

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Plum Health

MAY 19, 2023

Raquel Orlich treats a Plum Health member Are you a self-employed individual, uninsured, underinsured, or enrolled in a high deductible catastrophic health plan in the Detroit or Royal Oak area? While your insurance covers significant events, DPC takes care of routine healthcare needs affordably.

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Primary Care Insurance Medical Advice Healthcare 52

Plum Health

OCTOBER 29, 2024

Direct Access to Your Doctor : Many DPC providers limit their patient load, meaning you get more face-to-face time with your doctor, often with little to no wait time. Traditional primary care practices tend to have more patients, which can lead to longer wait times and potentially longer waits for appointments.

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BMJ

DECEMBER 16, 2021

We focus on five key areas and steps: 1) Deciding on the length of data collection, and timing and number of interviews; for example, researchers may consider whether the data collection points should be around researcher-led or participant-led key ‘events’ or at pre-established intervals. following individual or groups of participants).

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FDA Law

MARCH 7, 2024

NORD’s announcement followed in the footsteps of European rare disease patient organization, Eurodis , who had celebrated the first Rare Disease Day the year before. What started as a day has — due to its popularity and the persistent efforts of patients and industry — evolved into a week-long event.

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The Motivated MD

OCTOBER 10, 2024

With increasing emphasis on patient turnover and documentation, all while navigating the complexities of billing and authorization, our jobs are stressful and time-consuming. How, then, can any physician find the time to research individual companies and make educated decisions on which publicly traded businesses are undervalued?

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FDA Law

MARCH 7, 2024

Both documents discuss how membership should include individuals without conflicts of interest and with expertise in trial conduct, relevant clinical specialties, a qualified biostatistician, and a medical ethicist (in studies with greater risk).

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FDA Law

DECEMBER 7, 2022

In simple terms from a non-scientist, these gene therapies add functional versions of genes to patients that do not have them, and thus the idea is to have these genes function in the same way as they do in individuals without these disorders. they waned over time), even though patients would have benefited over a shorter duration?

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Permanente Medicine

MAY 20, 2025

Khang Nguyen, MD, chief transformation officer of the Southern California Permanente Medical Group, discusses how AI can increase clinicians’ joy in medicine and improve patient outcomes with Chris Grant, chief operating offer and executive vice president of Kaiser Permanente, The Permanente Federation, and host of the Permanente Medicine Podcast.

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Aspiring Minority Doctor

APRIL 18, 2021

In the event you are unsuccessful at extending your graduation date or securing an internship position, options for practicing medicine tend to become severely limited. It would also be possible to go into concierge medicine and focus on VIP patients. This would require relocating and I am not aware of how much it pays.

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GeriPal

MAY 19, 2022

A patient is on morphine and you want to convert it to another opioid like hydromorphone (dilaudid). Dr. Akhila Reddy and colleagues study looking at converting hospitalized cancer patients from IV hydromorphone to PO morphine, PO hydromorphone, or PO oxycodone. Step four is adjusting it for your patient. How do you do that?

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33 Charts

JANUARY 19, 2025

Consider a scenario where each one of the tens of thousands of doctors here begin creating posts twice a day 750 word creations that analyze or break down a timely event or research article. We’ll assume that they individually conceive and outline these posts, but that they’re heavily augmented by ChatGPT or Claude.

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Individual IT Patients 59

FDA Law

MARCH 8, 2023

eMDR submissions can be submitted in one of two ways: Health Level 7 Individual Case Safety Reports (HL7 ICSR) via AS2 (for high volume reporting) or by using FDA’s eSubmitter software (for low volume reporting). The eMDR requirements pertain to initial and supplemental MDRs and follow-up reports.

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Priority Physicians

JANUARY 27, 2025

In fact, for people who’ve experienced terrifying or anxiety-inducing events, therapists apply eye movement desensitization and reprocessing, or EMDR, a technique that mimics the patient’s REM-sleep eye movements, allowing them to “relive” and discuss the incident with decreased anxiety.) He completed his residency at St.

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Primary Care Doctor Primary Care Board-Certified Physicals 52

GeriPal

DECEMBER 2, 2022

So on today’s podcast we invite four brilliant individuals to talk about their perspective on how to change how we as a society and health care system partner with individuals with dementia. She directs UCSF MERI’s patient, family, and clinician support with classes and consultation on resiliency, well-being, and grief.

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Community IT Individual Patient-Centered 101

ABIM

APRIL 24, 2025

Expanding ABIM’s engagement with stakeholder communities such as early career physicians, specialty societies and patient-focused organizations. ABIM does not contact individual programs with a lower pass rate to initiate changes to the program. Jerome Clauser, Ed.D.,

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GeriPal

OCTOBER 13, 2022

When I’m on service these days there is inevitably a moment when a resident says “Patient so-and-so is on X” – and I have absolutely no idea what X is. Alex: And we are delighted to welcome Rasheeda Hall, who is a physician scientist in the division of nephrology at Duke University School of Medicine, and sees patients at the Durham VA.

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Complication Patient-Centered IT Patients 97

FDA Law

MAY 4, 2023

mobile applications to capture patient-reported outcomes through questionnaires). Dr. Sacks also explained that DHTs and DCTs may “open access to research” for older individuals and people with disabilities who are not able to travel to clinical trial sites, but could participate from home or a nearby clinic.

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Clinic Telehealth Provider Electronics 59

FDA Law

APRIL 23, 2023

This Draft Guidance focuses on the use of patient-level data from other clinical trials or from RWD sources. The goal is to select similar patients in the treatment and external control groups. The Draft Guidance also states that sponsors must include in their marketing applications relevant patient-level data for both arms.

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Patient-Centered Clinic Patients Provider 49

FDA Law

MAY 8, 2023

The discussion paper described a PCCP as including (1) the types of anticipated modifications (SaMD Pre-Specifications or SPS) based on the retraining and model update strategy and (2) the associated methodology (Algorithm Change Protocol or ACP) being used to implement those changes in a controlled manner to manage patient risks.

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Manufacturing Provider Medical IT 98

GeriPal

MAY 5, 2022

We talk with Nick and Meg about: Why hearing loss is important not just in geriatrics but also for those caring for seriously ill individuals. Communication techniques we can use when talking to individuals with hearing loss. But individuals who have hearing loss, there’s several problems. How to screen for hearing loss.

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IT Screening Hospital Clinic 102

FDA Law

NOVEMBER 1, 2023

The PR first sets out to establish that it has authority to regulate in vitro diagnostic “test systems” as devices, and not just the system’s individual components, such as reagents, instruments, specimen collection devices, and software.

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FDA Law

MAY 17, 2022

It’s the quinquennial event when many of the UFAs are up for reauthorization. FDA approved FIRDAPSE in November 2018, with a period of orphan drug exclusivity, for the treatment of Lambert-Eaton Myasthenic Syndrome (“LEMS”) in adult patients. Karst — We’re in the midst of UFA (User Fee Act) season! and more likely 15-20.

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FDA Law

FEBRUARY 27, 2024

156(c)(4) states that “in no event shall more than one patent be extended under subsection (e)(1) for the same regulatory review period for any product” (emphasis added). To that end, 35 U.S.C. § 156(c)(4) 8,173,663 with respect to NDA 022271 for NESINA (alogliptin) Tablets – see our previous post here ). sections l56(a)(5) and 156(f)(1).

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Patients IT Provider Individual 59

Pamela Wible MD

JUNE 20, 2025

Psychiatrists define burnout as a job-related dysphoria in an individual without major psychopathy—meaning you’re normal; your job is killing you. Moral injury is a normal human response to an abnormal traumatic event—a deep soul wound shattering one’s identity and morality. Let’s not waver on the truth.

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PEMBlog

OCTOBER 2, 2024

I’ll make the important distinction between gastritis – which is diagnosed only via endoscopy – and dyspepsia, the term best used to describe the symptoms many patients experience. Gastroesophageal reflux disease is when the patients have severe symptoms that persist and cause long term issues.

Diagnosis 52

Diagnosis Management IT Patient-Centered 52

Annals of Family Medicine

NOVEMBER 20, 2024

Methods: In-depth semi-structured interviews using the Database of Individual Patient Experiences (DIPEx) methodology. Participants were recruited via electronic healthcare records, community tabling events, and social media efforts. Verbatim transcripts in English and Spanish were analyzed in NVivo 14.

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Today's Hospitalist

JUNE 7, 2025

Medical societies and hospitals are weighing in on periprocedural concerns in patients taking GLP-1s who need procedures or surgeries. That’s according to two internists who work closely with hospitalized patients who take GLP-1s. These medications are truly life-changing for many patients.”

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Hospital Management Diabetes Patients 65

Physician's Weekly

JUNE 22, 2025

Targeted ICD selection based on predicted therapy benefit enhances patient outcomes while cutting hospital costs by 16.7%. Registry-based prediction models were applied to estimate individual prior probabilities.

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Hospital Individual Clinic Patients 52

Physician's Weekly

JUNE 14, 2025

The following is a summary of “ORAKLE: Optimal Risk prediction for mAke30 in patients with sepsis associated AKI using deep LEarning,” published in the May 2025 issue of Critical Care by Oh et al. Its performance was compared to Cox and XGBoost models. 0.86) for ORAKLE, 0.81 (95% CI: 0.79–0.83) 0.83) for XGBoost, and 0.80 (95% CI: 0.78–0.82)

Patient-Centered 52

Patient-Centered Patients Individual Clinic 52

Annals of Family Medicine

NOVEMBER 20, 2024

Using linked administrative databases, we identified all instances of PIP-AP according to the STOPP-START criteria, which have previously been shown to predict adverse clinical events such as ED visits and hospitalizations. Residents were followed for 1 year or to date of death, whichever occurred first.

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