Sat.Jan 11, 2025 - Fri.Jan 17, 2025

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Well-being Investment: Restorative Sleep - Foundation of Self-Care

Joy in Family Medicine Coaching

(NEW) TLDR at the bottom* Welcome back to our series on physical well-being investments. Today, we’re diving into perhaps the most critical supporter of self-care, the very foundation - restorative sleep. How challenging that can be in this line of work! If you’re already waking up refreshed and energized throughout the day—keep doing what works for you.

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Can Your Dinner Plate Predict Your Brain Health?

Dr. Shin's Notes

A groundbreaking study reveals that eating too much red meat—especially processed kinds—could increase your risk of dementia. But don’t worry, swapping these foods for healthier alternatives might not just save your memory but also keep your brain young. Red Meat and Dementia Risk Dr. Daniel Wang and his team at the Harvard T.H. Chan School… Read More » Can Your Dinner Plate Predict Your Brain Health?

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A chain reaction: HIV vaccines can lead to antibodies against antibodies

Medical Xpress

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection.

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Drugmakers hiked prices for hundreds of drugs in early January

NPR Health

January is a big time for drugmakers to hike prices. This year saw higher prices for 575 medications so far, including Ozempic, drugs for HIV, cancer and many others.

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Episode 374 – Rafael Medina Subspecialty Episode – Acute encephalopathy and unresponsiveness

The Clinical Problem Solvers

[link] In this Pulmonary & Critical Care episode, Dr. Meghan Nothem presents an unusual case of acute encephalopathy and unresponsiveness to Dr. Paul A. Bergl. Stay tuned to found out the final diagnosis! Session facilitator: Dr. Hui Ting Ruan Case discussant: Dr. Paul A. Bergl is an intensivist at Gundersen Lutheran Medical Center in La Crosse, WI and clinical adjunct assistant professor with the University of Wisconsin.

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To Be or Coco-Not To Be: That’s One Question Answered in FDA’s Final Guidance Documents on Food Allergens

FDA Law Blog

By Sophia R. Gaulkin & Ritte van Laack On January 6, 2025, FDA released two final guidance documents on food allergens: Questions and Answers Regarding Food Allergens, Including the Food Allergen Labeling Requirements of the Federal Food, Drug, and Cosmetic Act (Edition 5) , and Evaluating the Public Health Importance of Food Allergens Other Than the Major Food Allergens Listed in the Federal Food, Drug, and Cosmetic Act.

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Specific neurons with an immune 'doorbell' may influence mood and memory

Medical Xpress

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states. In disease, high levels of IL-1 in the brain are linked to neuroinflammation, which can disrupt the body's stress response, cause sickness-like behaviors, worsen inflammation by activating brain immune cells, and allow immune cells from the body to enter the brain.

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#HPMParty is Back in Denver for the 2025 AAHPM-HPNA Annual Assembly

GeriPal

The #HPMParty is returning to Denver during the 2025 AAHPM/HPNA Annual Assembly. We will be doing our traditional Pub Crawl, this time starting at 8 pm on Thursday, February 6th at the Celtic on the corner of 14th and Market in historic LoDo. From the Celtic, we will move on to the next location at 10 pm-ish (location is TBD). With that said, exact times and locations are subject to change, so go to geripal.org or follow the hashtag #HPMparty on Twitter or Bluesky for updates along the way.

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FDA’s Issues Draft Guidance on Accelerated Approval: A Substantial Evidentiary and Procedural Overhaul to this High-Profile Pathway

FDA Law Blog

By Charles G. Raver & James E. Valentine & Ellis Unger & Frank J. Sasinowski On December 5, 2024, FDA published a new draft guidance on accelerated approval providing a much needed and substantial update to its guidance on the pathway. FDAs application and use of accelerated approval has evolved dramatically since it was first developed by the Agency to help address the HIV/AIDS epidemic in the late 1980s.

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New article warns against restricting discussions on structural racism

Medical Xpress

A new Health Affairs article highlights the detrimental impact of recent state and federal policies that restrict discussions of "divisive concepts," including structural racism. It warns that these policies undermine efforts to address health inequities and improve population health.

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Amid the fires, LA is warning some residents the tap water isn't safe. Here's why

NPR Health

Wildfires have a history of causing problems with the drinking water systems. In some affected areas around LA, officials are warning residents not to drink from the tap or even to shower.

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Finishing Well

Evergreen Family Medicine

It’s been 45 years. I’ve had that long to consider health care in Douglas County. What we do well. What we don’t. Time to observe the impact of technology on health care for both good and bad, and to assimilate the cultural changes in physicians and society that influence how we relate to one another. I've had time to think about what matters most and what control I have over other people’s health and happiness.

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HPM Grows Its Ranks of Directors, Counsel, and Associates as it begins its 45th Anniversary Year

FDA Law Blog

Hyman, Phelps & McNamara PC, (HPM), which will mark its 45thAnniversary on March 17, 2025, is pleased to announce that it is increasing its directors, counsel, and associates as it starts the year. Kalie E. Richardson has been promoted to Director. Mark Tobolowsky has been promoted to Counsel; and Esther Petrikovsky is joining the firm as an Associate.

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Retinal neurons provide insight into schizophrenia disease mechanisms

Medical Xpress

Researchers analyzed the genetic connection of retinal cells and several neuropsychiatric disorders. By combining different datasets, they found that schizophrenia risk genes were associated with specific neurons in the retina. The involved risk genes suggest an impairment of synapse biology, so the ability of neurons to communicate with each other.

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The FDA calls for at-a-glance nutrition labels on the front of packaged foods

NPR Health

The FDA wants front-of-package nutrition labels required on packaged foods. The labels would tell consumers if the product has Low, Medium or High levels of saturated fat, sodium and added sugar.

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PSA screening: shared decision making is a flawed approach

Common Sense Family Doctor

In early 2020, I accepted an invitation to participate in a live debate with a nationally prominent academic urologist at the annual scientific meeting of the American Society for Men's Health. The topic: "The Great Debate of the 21st Century: To PSA screen or not to screen." Unfortunately, the COVID-19 pandemic caused the meeting to the canceled. By the time I was re-invited in 2021, my academic interests had drifted away from prostate cancer screening, so I declined.

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Is FDA Man’s Best Friend’s Best Friend?

FDA Law Blog

By Charles D. Snow & Sara W. Koblitz On January 7, 2025, FDA announced that back on November 12, 2024, the Center for Veterinary Medicine (CVM) issued Warning Letters to six online retailers marketing unapproved new animal drug products that purported to treat and control seizures and epilepsy in dogs and cats. At minimum, this autumnal burst of Warning Letters from CVM is notable because CVM only issued a total of 22 Warning Letters in 2024at least that have been made public by the Agency.

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The power of cinema: Study shows film intervention reduces violence against children

Medical Xpress

A new study shows that screenings of a locally-produced narrative film about parenting led to a significant reduction in physical violence against children.

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Hazmat crews tackle toxic waste left behind by LA's fires

NPR Health

The fires have turned some electric car batteries and household items into "unexploded ordnances," says an EPA official tasked with the cleanup (Image credit: David Crane/MediaNews Group)

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In case you missed it: A podcast on norovirus

PEMBlog

Here in early 2025 we are seeing a norovirus outbreak in the United States. That’s a lot of vomiting and diarrhea. I wanted to share my podcast episode on norovirus that is only 7 minutes and 13 seconds long! If you listen at 1.5x speed – I know there are those of you out there – that’s only 4 minutes and 49 seconds. If you listen at 2x you’re a sicko… You can find PEM Currents: The Pediatric Emergency Medicine Podcast wherever you listen and subscribe to podc

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As 2024 Closed, FDA Issued a Proposed Rule on Asbestos Testing; Implementation of MoCRA Remains Much Slower Than Planned

FDA Law Blog

By Ritte van Laack A little over two years ago, the Modernization of Cosmetic Regulation Act (MoCRA) was (at long last) enacted. The passing of the law which, among other things, amended the Federal Food, Drug, and Cosmetic Act to include requirements for facility registration and product listing, safety substantiation, adverse event reporting, and requirements for FDA to issue several new regulations, brought excitement and anxiety.

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AI can guide acquisition of diagnostic-quality lung ultrasound images

Medical Xpress

Trained health care professionals (THCPs), including medical assistants, respiratory therapists, and nurses, with artificial intelligence (AI) assistance can achieve lung ultrasound (LUS) images with diagnostic quality that does not differ significantly from that achieved by experts, according to a study published online Jan. 15 in JAMA Cardiology.

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Move aside BMI: There's a better way to define obesity, commission finds

NPR Health

An international committee of scientists has proposed changing the way obesity is defined and diagnosed. The proposal adds more ways to measure body composition and fat.

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Medical Music Mondays: So Appy to See You

PEMBlog

Appendicitis! Rock Opera! McBurney’s point! Epic! Lyrics [Chorus] So Appy to see you Said the Surgeon to the doc Take out that appendix while I’m on the clock [Verse] Pain was vague then moved last night In the quadrant lower right Vomit and some hopping pain A fever now, can you explain? McBurney’s point and rebound Next step is an ultrasound Call the surgeon, call them quick Appendicitis made him sick [Chorus} So Appy to see you Said the Surgeon to the doc Take out that appen

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Mitochondrial Uncouplers: The Future of Weight Loss Medications?

Clinical Correlations

By Ella Feiner Peer Reviewed In a world abundant with food and sedentary lifestyles, the global prevalence of cardiometabolic disease has reached alarming levels.

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Interdisciplinary research lays groundwork for predicting if bone cancer will spread

Medical Xpress

Bone pain. Joint pain. Bone swelling. These are symptoms that about 1,000 people in the United States begin to feel each year shortly before being diagnosed with osteosarcoma, a type of cancer that starts in the bones. Although any age can develop osteosarcoma, approximately half of diagnosed cases are in children and adolescents.

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The Princess of Wales says her cancer is in remission

NPR Health

The Princess of Wales revealed that her cancer is in remission after an emotional visit to the hospital where she received treatment last year.

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Caring for the Unrepresented: A Podcast with Joe Dixon, Timothy Farrell, Yael Zweig

GeriPal

Summary Transcript CME Summary Many older adults lose decision-making capacity during serious illnesses, and a significant percentage lack family or friends to assist with decisions. These individuals may become unrepresented, meaning they lack the capacity to make a specific medical decision, do not have an advance directive for that decision, and do not have a surrogate to help.

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A Podcast on Inhalant Misuse: From Glue to Galaxy Gas

PEMBlog

In this episode of PEM Currents: The Pediatric Emergency Medicine Podcast , we explore the complex and often underrecognized issue of inhalant misuse. From the early days of glue sniffing to the recent rise of nitrous oxide misuse, fueled by brands like Galaxy Gas and viral trends on TikTok and Instagram, inhalant misuse has evolved into a growing concern among adolescents.

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Megakaryocytes' immune characteristics and role elucidated

Medical Xpress

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts. Recent advances in technology have unveiled the diverse immune functions of MKs, which express immune sensors and participate in immune activities, thus expanding their traditional role beyond hemostasis and coagulation.

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Lower nicotine requirements in cigarettes could be coming soon

NPR Health

The FDA is expected to propose a new rule Wednesday that would mean cigarettes have lower nicotine limits to make them less addictive.

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On Apache lands, progress in a long war against ticks and the disease they spread

NPR Health

Rocky Mountain Spotted Fever, the deadliest tick-borne disease in the U.S., is a big problem on tribal lands in the Southwest. A community-led response on Apache lands in Arizona is helping save lives.

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Biden's Medicaid director shares lessons learned and concerns for the program's future

NPR Health

Dan Tsai discusses how he ran Medicaid under Biden, and his fears for how Republicans might try to change the program.

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New animal model offers insights into pancreatic disease and diabetes

Medical Xpress

Cystic fibrosis (CF) is a life-threatening genetic disease affecting multiple organ systems, with pancreatic dysfunction representing a critical and often overlooked complication. A recent study published in eGastroenterology introduces young rabbits with CF as a novel and accessible model to study CF-related pancreatic endocrine pathology. This model offers an unprecedented opportunity to deepen our understanding of CF-related diabetes (CFRD), a condition affecting up to 50% of adults with CF.

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Pandemic led to rapid adoption of telemental health for those with schizophrenia

Medical Xpress

For Medicaid beneficiaries with schizophrenia, delivery of mental health care through telehealth (telemental health care) diffused rapidly after onset of the COVID-19 pandemic, according to a study published online Jan. 16 in JAMA Network Open.

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How soda is changing the world

NPR Health

A new study establishes that soda consumption is doing ever more damage to health with rising rates of diabetes in regions where soda-drinking is on the rise, like sub-Saharan Africa.

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Early pregnancy weight gain tied to fetal fat buildup

Medical Xpress

Fetuses of pregnant people who gained excess weight in the first trimester of pregnancy show signs of excess fat distribution in the upper arm and in the abdomen, according to a study by researchers at the National Institutes of Health. These findings may inform efforts to prevent excessive weight gain early in life, a risk factor for adult obesity and related conditions, such as heart disease, high blood pressure and diabetes.