Fri.Apr 18, 2025

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N-cadherin triggers neural stem cell differentiation: Discovery shows potential for brain aging and disease therapies

Medical Xpress

Northeastern University scientists have discovered that a protein in the human brain could potentially be used to grow new neurons in the lab and enhance brain processes affected by aging or neurodegenerative diseases.

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Remembering Holly J. Humphrey, MD, MACP

ABIM

A Message from Furman S. McDonald, President and CEO of ABIM and the ABIM Foundation ABIM has lost a true friend and valued colleague. Holly J. Humphrey, MD, MACP, a nationally renowned leader in medical education and President of the Josiah Macy Jr. Foundation, passed yesterday from pancreatic cancer. Holly had a long and meaningful relationship with ABIM dating back to her first days on the ABIM Board of Directors in 2001.

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Common antiparasitic drug shows promise in halting growth of aggressive skin cancer

Medical Xpress

A common pinworm medication may stop and reverse cancer growth in Merkel cell carcinoma, an aggressive form of skin cancer, according to research led by University of Arizona Cancer Center researchers and published in the Journal of Clinical Investigation.

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How FDA cuts could make the food and drug supply less safe

NPR Health

While Food and Drug Administration inspectors who make sure food and drugs meet quality standards were spared in recent cuts, key support staffers were dismissed.

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Key enzyme in lipid metabolism linked to immune system aging

Medical Xpress

Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren't completely sure why. They may have a better idea now, however, thanks to a study in GeroScience.

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You're probably taking over-the-counter painkillers incorrectly

NPR Health

People often use the wrong painkiller or take too much too quickly, increasing the risk of side effects, say pharmacists. Here are safer and more effective ways to take drugs like Advil and Tylenol.

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Colder temperatures increase gastroenteritis risk in Rohingya refugee camps, study shows

Medical Xpress

A new study by scientists at Hokkaido University has found that lower temperatures significantly increase the risk of gastroenteritis among Rohingya refugees living in Bangladesh's Kutupalong and Nayapara camps. Gastroenteritis is a viral or bacterial infection that causes inflammation of the stomach and intestines, resulting in diarrhea, vomiting, and stomach pain.

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GLP-1 therapies show potential for treating rare genetic disorder Bardet-Biedl syndrome

Medical Xpress

A Monell Chemical Senses Center study published this week in the Journal of Clinical Investigation offers renewed hope for individuals living with Bardet-Biedl Syndrome (BBS), a rare genetic disorder characterized by early-onset obesity, compulsive eating, and cognitive impairments.

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Into dudes who drum? You might be a female fiddler crab

NPR Health

Afruca tangeri ) lives along the Atlantic coast, from Portugal in southwestern Europe to Angola in western Africa. Male crabs have one small claw and one big claw that they use in their dances to attract a mate.'/> The male European fiddler crab attracts his mate by performing a courtship dance. New research published in the Journal of Experimental Biology says that dance isn't just notable for its visuals it's notable for its vibrations, too.

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Top NIH nutrition researcher quits, citing censorship under Kennedy

Medical Xpress

A senior government health researcher has announced his retirement, accusing the National Institutes of Health (NIH) of censoring his latest findings on ultra-processed food.

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The CDC staff in charge of injury prevention — a lead cause of death — has been cut

NPR Health

Injury is the leading cause of death for people under the age of 45. But much of the staff at the CDC responsible for studying how to track and prevent injuries were cut during the recent firings.

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Research identifies new cut-off points for overweight and obesity in male athletes

Medical Xpress

New research presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 1114 May) shows that the internationally recognized body mass index (BMI) cut-off points greatly overestimate overweight and obesity in male athletes. The study, from Italy, also proposes new cut-off points for overweight and obesity in this group.

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'Lab Leak,' a flashy page on the virus' origins, replaces government COVID sites

NPR Health

The new page emphatically promotes a theory that many scientists question. Meanwhile, basic information about COVID testing and vaccines has disappeared. (Image credit: Whitehouse.

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First weight-loss pill from Lilly shows promising results

Medical Xpress

A new pill designed to help with weight loss and blood sugar control is showing promise in early studies.

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For advances in treating ACL injuries, look to dogs

Medical Xpress

Even after surgery, injuries to the anterior cruciate ligament (ACL) often lead to chronic pain and reduced mobility, with limited options for treatment. New research suggests that advances in knowledge and therapeutics may come from an unlikely source: dogs.

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Q&A: How much protein do I really need?

Medical Xpress

New protein-enriched products are hitting grocery store shelves and being advertised seemingly every day, while diets prioritizing protein make the rounds on social media.

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Science-backed exercise therapy improves low back pain

Medical Xpress

Research supports the effectiveness of a kinesiology-based method to treat lower back pain, say study authors working in collaboration with the National Research Council of Italy, and scientists at the Sbarro Health Research Organization under the leadership of its Founder and President, Antonio Giordano, M.D., Ph.D., Professor at Temple University.

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Novel radiolabeled antibody developed for diagnosis and treatment of solid tumors

Medical Xpress

A newly developed radiolabeled antibody that targets the cancer antigen IL13R2 has been found to be highly specific, binding only to cancer cells and not to the related antigen IL13R1, which is widely expressed in healthy tissues. Tested in multiple cancer types, the radiolabeled antibody was effective at delineating malignancies at a low injected mass dose and has the potential to be translated into radioimmunotherapy applications.

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Global telemedicine therapy for dementia shows benefit in clinical trial

Medical Xpress

For people living with primary progressive aphasia (PPA), a rare, early-onset neurodegenerative dementia that predominantly affects language abilities, something as simple as ordering their favorite meal at a drive-thru can be a deeply meaningful marker of independence.

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Analysis reveals rise in claim denial rates for cancer-related advanced genetic testing

Medical Xpress

Both the use of next-generation sequencing (NGS) testing for cancer and the rate of claim denials for such testing increased between 2016 and 2021, despite implementation of a recent Medicare national coverage determination that established coverage standards for NGS testing.

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AI analyzes chest radiographs to quickly shortlist potential matches in forensic cases

Medical Xpress

An interdisciplinary team comprising faculty and doctoral students from the Department of Anthropology and Computer Science and Engineering has found a way to use artificial intelligence (AI) to help forensic anthropologists identify individuals faster and more efficiently.

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Rare variants in GPKOW associated with multisystemic X-linked developmental disorder

Medical Xpress

A new study published in Genetics in Medicine identifies a novel disease-associated gene, GPKOW, that plays an important role in the development of the brain, eyes and other organ systems. Researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital and collaborating institutions show that rare variants in GPKOW, a gene on the X-chromosome, cause a severe multisystemic syndrome resulting in restricted fetal growth, sm

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Study finds women much more likely to be aware of and have good understanding of obesity drugs

Medical Xpress

New research being presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 1114 May) shows that women are much more aware of and knowledgeable about the obesity drugs GLP-1/GIP receptor agonists (that include semaglutide and tirzepatide).

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Low-income patients with diabetes are more likely to experience insurance instability, researchers find

Medical Xpress

An Oregon Health & Science University-led study reveals that low-income adults with diabetes are more likely to go in and out of health insurance, and that insurance instability is even worse for those with complex needs.

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Detecting invasive nodules could be key to preventing unnecessary pancreatic cancer surgery

Medical Xpress

Pancreatic cysts are fluid-filled sacs that can form in the pancreas. Some remain benign, while others have the potential to develop into pancreatic cancer. A recent study, which followed 257 patients in Japan for an average of five years, showed that the presence or absence of invasive nodules in pancreatic cysts is key to assessing whether these cysts are benign or cancerous.

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Research identifies key enzyme target to fight deadly brain cancers

Medical Xpress

Researchers have found that targeting an enzyme called PGM3 can help stop the growth of glioblastoma, the most dangerous type of brain tumor. Study findings are published online in the journal Science Advances.

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Study highlights gaps in firearm suicide prevention among women

Medical Xpress

Just under 4 in 10 women who died by firearm suicide had no documented history of mental or physical health problems in a new study, highlighting a need for prevention strategies tailored to at-risk women.

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Modeling shows clean water and sanitation reduce cholera transmission where disease is entrenched

Medical Xpress

Public health strategies, from vaccination to improving sanitary conditions, may have different impacts depending on whether a disease is endemicpersisting in a particular location for an extended period of timeor a new outbreak, because the dominant transmission routes may differ, according to a new study.