Joy in Family Medicine Coaching

DECEMBER 6, 2024

We are continuing our series involving your ideal future in medicine. For those of you out there saying, “Enough with the dreaming and mindset stuff; I want to take action,” this is your month! If you haven’t already, write your goals and the vision behind them. You can use the steps I gave three weeks ago. Now, I’m going to encourage something contrary to my typical suggestions.

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Private Practice Primary Care IT Education 130

Medical Xpress

DECEMBER 6, 2024

There is a U-shaped association between alcohol consumption and coronary heart disease (CHD) and type 2 diabetes (T2D) but no evidence for a causal association, according to a study published online Nov. 24 in Alcohol: Clinical and Experimental Research.

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Diabetes Clinic 105

FDA Law Blog

DECEMBER 6, 2024

By Mark A. Tobolowsky & Charles G. Raver & James E. Valentine On November 19, 2024, FDA released a draft guidance titled Frequently Asked Questions Developing Potential Cellular and Gene Therapy Products. As much of the content of this draft guidance for cellular and gene therapy (CGT) products is articulated elsewhere, this document serves as a one-stop shop or Cliffs Notes for the numerous guidance documents now covering CGT product development.

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Clinic Provider IT Electronics 59

Medical Xpress

DECEMBER 6, 2024

Brainmachine interfaces (BMIs) have enabled a handful of test participants who are unable to move or speak to communicate simply by thinking. An implanted device picks up the neural signals associated with a particular thought and converts them into control signals that are fed into a computer or a robotic limb. For example, a quadriplegic person is asked to think about moving a cursor on a computer screen.

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Screening 96

The Clinical Problem Solvers

DECEMBER 6, 2024

[link] In this dermatology episode, Dr. Eamonn Maher presents a case of eruptive nodules to Dr. Steven Chen. Session facilitator: Dr. Maddy Conte Case Discussant: Dr. Steven Chen Case Presenter: Dr. Eamonn Maher Evolution of Skin Lesions: Link here Skin Biopsies: Link here To join us live and present a case, check out our virtual morning reports !

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Medical Xpress

DECEMBER 6, 2024

A breakthrough by researchers at Peter Mac will allow scientists to detect, analyze and profile cancer tumors in patients via a simple blood test. The Dawson lab at Peter Mac has developed a method that can take circulating tumor DNA (ctDNA) from the patient's blood and use an algorithm to identify cancer-related changes and patterns in their DNA.

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Patients 85

Medical Xpress

DECEMBER 6, 2024

According to a new study published in Nature Communications, researchers at the Department of Laboratory Medicine, Karolinska Institutet, have made a significant leap in drug discovery and development with a new method called CeTEAM. This approach connects how drugs bind to their targets inside cells with the effects they produce, offering a clearer understanding of how a drug works.

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Medical 85

Medical Xpress

DECEMBER 6, 2024

Researchers have discovered that astrocytes play an important role in regulating stress responses in the lateral septum in the brain. It is expected to provide new clues for mental health treatments.

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Mental Health Provider IT 81

Medical Xpress

DECEMBER 6, 2024

Exactly why do people remember what they remember? A recently published review paper from researchers at Rice University sheds light on this fundamental question and the relationship between factors that influence human memory.

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Relationship 81

Medical Xpress

DECEMBER 6, 2024

Cleveland Clinic Genome Center researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study, published in the journal Alzheimer's & Dementia, also integrates drug databases with real-world patient data to identify FDA-approved drugs that may be repurposed to target disease-associated microglia in Alzheimer's disease without affecting the healthy type.

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Patient-Centered Clinic Patients 81

Medical Xpress

DECEMBER 6, 2024

A significant advance in breast cancer research has uncovered a key mechanism driving cancer invasion and drug resistance. A University of Liverpool study reveals how two critical molecules present in "HER2-positive" breast cancerone of the most aggressive formsinfluence breast cancer survival and its spread. The findings are published in the journal Science Advances.

IT 81

IT 81

Medical Xpress

DECEMBER 6, 2024

Genicular artery embolization (GEA) is effective and safe for reducing osteoarthritis (OA) symptoms among patients with knee OA that is refractory to conservative therapy, according to a study presented at the annual meeting of the Radiological Society of North America, held from Dec. 1 to 5 in Chicago.

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Patients 80

Medical Xpress

DECEMBER 6, 2024

Experts have used magnetic resonance imaging (MRI) to better understand the impact a gluten free diet has on people with celiac disease, which could be the first step towards finding new ways of treating the condition.

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Medical Xpress

DECEMBER 6, 2024

The gut microbiota might perhaps one day become a routine tool for the early diagnosis of many diseases and to guide treatment, but at present there is a lack of solid scientific evidence to support these claims. Yet, day by day, there are more and more offers of commercial kits for do-it-yourself testing, at the moment totally lacking in meaning and scientific solidity.

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Diagnosis IT Medical 75

Medical Xpress

DECEMBER 6, 2024

As in most years that we've followed news reporting about the myth that suicides peak during the end-of-year holidays, an analysis of the past year showed again that more newspaper accounts supported the false idea that the suicide rate increases during the holiday season than debunked it.

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IT 75

Medical Xpress

DECEMBER 6, 2024

Research led by The Ohio State University Wexner Medical Center and College of Medicine along with scientists at the CharitUniversittsmedizin Berlin in Berlin, Germany, provides first evidence that hospital-acquired pressure ulcers are a potent risk factor for poor neurological recovery among patients with acute spinal cord injury (SCI).

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Patients Patient-Centered Hospital Provider 75

Medical Xpress

DECEMBER 6, 2024

Through a series of cell and animal studies, a research team has identified the principal culprit causing flare-ups in patients with a rare genetic disorder called fibrodysplasia ossificans progressiva.

Patients 75

Patients 75

Medical Xpress

DECEMBER 6, 2024

Kumamoto University scientists have unveiled a novel compound, HPH-15, with dual effects of reducing blood glucose levels and combating fat accumulation, marking a significant leap in diabetes treatment innovation.

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Diabetes 75

Medical Xpress

DECEMBER 6, 2024

A bonus round of talks striving to finish a landmark global agreement on handling future pandemics was set to close Friday without a breakthrough.

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Medical Xpress

DECEMBER 6, 2024

The World Health Organization said Friday it was deploying experts to investigate a mystery flu-like illness that has killed dozens of people in southwest Congo in recent weeks.

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Illness IT 74

Medical Xpress

DECEMBER 6, 2024

The prevalence of Meniere disease is higher in people with atopic dermatitis (AD), according to a study published online Nov. 12 in The Laryngoscope.

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Patients 74

Medical Xpress

DECEMBER 6, 2024

Severe hemophilia A is a genetic disorder that prevents blood from clotting properly, posing a constant risk of dangerous bleeding episodes. Infants with severe hemophilia A (HA) are at risk of brain bleeds, which can lead to serious long-term brain damage. Emicizumab (Hemlibra) was approved by the FDA in 2018 to prevent and reduce bleeding for patients who suffer from hemophilia A.

Patients 74

Patients 74

Medical Xpress

DECEMBER 6, 2024

People are accepting of and prefer self-testing for human papilloma virus (HPV), rather than having a clinician-led cervical smear test, but there is a lack of knowledge about the new cervical screening process, University of Otagotkou Whakaihu Waka research shows.

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Screening 73

Medical Xpress

DECEMBER 6, 2024

Noninferiority of reduced- versus full-dose anticoagulants cannot be proven in patients with venous thromboembolism who need extended anticoagulation, according to a study to be presented at the annual meeting of the American Society of Hematology, held from Dec. 7 to 10 in San Diego.

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Patients 52

Medical Xpress

DECEMBER 6, 2024

As the EU's population ages, health care demand is set to rise. New projections suggest that, if current disease prevalence remains constant, doctor and nurse numbers would need to increase by 30% and 33% respectively by 2071 to meet demand. However, healthy aging could significantly reduce this need.

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Medical 45

Medical Xpress

DECEMBER 6, 2024

For asymptomatic rheumatoid arthritis (RA) patients, a new radiation-free screening protocol can identify suspected interstitial lung involvement (ILI), according to a study published online Nov. 23 in BMC Pulmonary Medicine.

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Screening Patients 45

Medical Xpress

DECEMBER 6, 2024

Many women with epilepsy who are of childbearing age might not realize their anti-seizure drugs can raise the risk of birth defects or dampen the effectiveness of their birth control, a new study warns.

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Medical Xpress

DECEMBER 6, 2024

Autologous hematopoietic cell transplant (auto-HCT) is not beneficial for patients with mantle cell lymphoma (MCL) in first complete remission (CR) with undetectable minimal residual disease (uMRD), according to a study to be presented at the annual meeting of the American Society of Hematology, held from Dec. 7 to 10 in San Diego.

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Patients 40

Medical Xpress

DECEMBER 6, 2024

From January through June 2024, 7.9% of people of all ages in the United States were uninsured, according to a report published online Dec. 6 by the National Center for Health Statistics.

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Medical 40

Medical Xpress

DECEMBER 6, 2024

Endoscopic full-thickness plication (EFTP), which improves the valvular mechanism of the gastroesophageal junction, is efficacious for managing gastroesophageal reflux disease (GERD) symptoms, according to research published in the November issue of JGH Open.

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Management 40

Medical Xpress

DECEMBER 6, 2024

Pancreatic cancer has recently been included in the list of diseases about which Brazil's National Cancer Institute (INCA) periodically publishes statistics. Although it is not the most frequent type of cancer, its high lethality makes it one of the leading causes of death from cancer in Brazil, partly owing to late diagnosis.

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Diagnosis Patients IT 73

Medical Xpress

DECEMBER 6, 2024

Researchers at The Jackson Laboratory and Trudeau Institute have identified the first mouse strain that is susceptible to severe COVID-19 without the need for genetic modification. This development, reported in Scientific Reports, marks a pivotal step forward in infectious disease research, providing an essential tool to develop vaccines and therapeutics for future coronavirus variants and potential pandemics.

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Vaccination Provider Medical 99