Sat.Jul 05, 2025

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How subjective likability practices undermine Canada’s health workforce recruitment and retention

KevinMD

In the face of worsening health workforce shortages, Canada must shift from a culture of personal likability to a system of objective qualifications or merits in recruiting and retaining physicians. While team cohesion and interpersonal compatibility are essential, an overemphasis on “fit” or likability excludes talented physicians, particularly immigrants and racialized minorities, who may not Read more… How subjective likability practices undermine Canada’s health workforce r

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Pretreatment LDH and SII Predict Survival in Melanoma

Physician's Weekly

Baseline LDH and SII levels emerged as key predictors of survival outcomes in individuals with advanced melanoma receiving first-line anti-PD-1 therapy. Researchers conducted a retrospective study published in June 2025 issue of International Journal of Dermatology to identify potential biomarkers associated with objective response (ORR), progression-free survival (PFS), and overall survival (OS) in individuals receiving first-line anti–PD-1 immunotherapy for advanced melanoma.

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Why medical schools must ditch lectures and embrace active learning

KevinMD

When I was a medical student, some enterprising classmate started a note taking service so we wouldn’t have to take notes on our own. He set up a tape recorder and transcribed the notes for distribution the next day. One day, our professor showed up with a tape recorder, set it up on the table Read more… Why medical schools must ditch lectures and embrace active learning originally appeared in KevinMD.com.

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Exploring Care Needs in Persistent Depressive Disorder

Physician's Weekly

Self-management and caregiver support emerged as key needs for individuals with persistent depressive disorder, highlighting gaps in current care practices. Researchers conducted a retrospective study published in June 2025 issue of Frontiers in Psychiatry to explore the role of self-management interventions involving informal caregivers for individuals with persistent depres sive disorder (PDD) – a chronic form of depres sion – secondary mental healthcare who did not respond adeq

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How to Start Virtual Care the Right Way: A Proven Roadmap for 2025 and Beyond

Speaker: Dr. Christine Gall, DrPH, MS, BSN, RN

The promise of virtual care is no longer theoretical and is now a critical solution to many of healthcare’s most urgent challenges. Yet many healthcare leaders remain unsure how to build a business case for investment and launching the right program at the right time can be the difference between value and failure. For organizations seeking a financially sound, clinically effective entry point, Virtual Patient Observation (VPO) offers a compelling case to lead with.

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Why judgment is hurting doctors—and how mindfulness can heal

KevinMD

Judgment pervades medicine—of patients, colleagues, and ourselves. We’re trained to judge, disguised as caring, standards, and competence. It’s seen as essential to being a “good physician.” We do it so instinctively, we rarely question it. But we should. The culture of judgment in medicine Judgment is baked into our training: The scrutiny of rounds, the Read more… Why judgment is hurting doctors—and how mindfulness can heal originally appeared in KevinMD.com.

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Mental Health Care Barriers Impact Pediatric Hospital Stays

Physician's Weekly

Prolonged pediatric hospital stays were driven by systemic gaps and complex psychiatric needs, underscoring the urgency for coordinated mental health discharge solutions. Researchers conducted a retrospective study published in June 2025 issue of Journal of Pediatrics to identify factors associated with prolonged length of hospital stay (LOS) and delayed discharges (DD) among children referred to Pediatric Consultation-Liaison Psychiatry Services (PLPS) in a tertiary hospital in Ireland.

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Exploring Gaps in Dialysis Self-Management Interventions

Physician's Weekly

Self-management trials in hemodialysis revealed key gaps and new priorities, spotlighting overlooked areas like infection control and stress management. The study published in the June 2025 issue of BMC Nephrology indicated that self-management was important to lower health risks in individuals on hemodialysis, but many showed poor adherence, highlighting the need for improved support through targeted interventions.

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Why helping people means more than getting an MD

KevinMD

“Why do you want to be a doctor?” Ask any pre-med that question, and you’ll probably hear the same answer: “I just want to help people.” I’ve said it, too—more times than I can count. But lately, I’ve started to question what that phrase even means. Not because I’ve lost faith in medicine, but because Read more… Why helping people means more than getting an MD originally appeared in KevinMD.com.

IT 169
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Diaphragm Drive Predicts Ventilatory Load Tolerance

Physician's Weekly

Neuro-ventilatory coupling rose with reduced pressure support, revealing diaphragm readiness for ventilator liberation in ICU care. A study published in June 2025 issue of Critical Care highlighted the importance of aligning ventilatory support with neural respiratory drive (NRD) to prevent diaphragm dysfunction in individuals of intensive care units (ICU).

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Episode 406 – Spaced Learning Series – Flank Pain, Hypercalcemia, and Granulomas

The Clinical Problem Solvers

[link] Episode description: A fascinating case that started as flank pain … ultimately seen in outpatient pulmonology! Join us for this adventure in clinical reasoning. Featuring: Priyanka Athavale Anna Fretz Kirtan Patolia Seyma Yildirim Schemas: Flank Pain Hypercalcemia Granulomas Download CPSolvers App here RLRCPSOLVERS Click here to view the weekly episode recap email!

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Regional Cancer Risk Reflects Social Vulnerability

Physician's Weekly

Counties in low-GDP states face higher cancer mortality, shaped by structural inequities and social vulnerability. Researchers conducted a retrospective study published in June 2025 issue of American Journal of Surgery to identify county-level mortality hotspots for breast, colorectal, lung, and prostate cancers and examine the influence of structural factors and the Social Vulnerability Index (SVI) on racial and ethnic disparities.

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Cuts to HIV research funding in the US impacts progress towards ending the epidemic

NPR Health

How will the Trump administration's cuts to HIV research impact the progress that's been made towards ending the epidemic in the U.S.?

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Novel Scoring System Accurately Tracks Crohn’s Ulcers

Physician's Weekly

A validated scoring tool, EASE-CD, showed strong accuracy and reliability in quantifying ulcer activity in Crohn’s disease. Researchers conducted a retrospective study published in June 2025 issue of Lancet Gastroenterology and Hepatology to develop and validate a new endoscopic index for Crohn’s disease addressing limitations of existing scoring systems.

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Neuromuscular Training Reduces Pain Facilitation After TKA

Physician's Weekly

Combined neuromuscular training and pain education reduced elevated pain responses in individuals with persistent pain after knee replacement. A study published in June 2025 issue of European Journal of Pain emphasized that around 15%–20% of individuals undergoing surgery experience chronic pain following total knee arthroplasty (TKA), with underlying causes remaining unclear but potentially linked to central sensitization and psychosocial influences.

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Evaluating Recurrence Risk After Initial TURBT in HG Ta

Physician's Weekly

Second-look TURBT showed limited value in altering outcomes for high-grade Ta bladder cancer after complete resection. Researchers conducted a retrospective study published in the June 2025 issue of World Journal of Urology to evaluate the prognostic impact of restaging transurethral resection (TURBT) in individuals with high-grade (HG) Ta bladder cancer that was completely resected during the initial procedure.

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High Mortality With ECMO in Cystic Fibrosis Exacerbations

Physician's Weekly

ECMO use in cystic fibrosis with severe respiratory failure showed limited survival, highlighting the need for cautious clinical decision-making. Researchers conducted a retrospective study published in June 2025 issue of BMC Pulmonary Medicine to examine the role of extracorporeal membrane oxygenation (ECMO) in individuals with cystic fibrosis (CF) and severe respiratory failure requiring invasive mechanical ventilation.

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Neuroinflammatory Impact of a CFI Variant

Physician's Weekly

A rare CFI variant linked to severe neuroinflammation was found to be highly enriched in the Old Order Amish population. A study published in June 2025 issue of Journal of Allergy and clinical Immunology highlighted complement factor I (CFI) deficiency as an ultra-rare inherited disorder of complement regulation characterized by diverse infectious, vasculitic, and neuroinflammatory manifestations.

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Targeted Therapies for Checkpoint Inhibitor Toxicities

Physician's Weekly

Emerging evidence indicates JAK inhibitors could be a valuable alternative for managing checkpoint inhibitor–induced immune toxicities, especially in difficult-to-treat cases. Researchers conducted a retrospective study published in June 2025 issue of Rheumatology to describe the role of JAK inhibitors in managing immune-mediated adverse events (AEs), based on a review of published case reports.

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Incidence and Predictors of Atrial Fibrillation in ATTRwt

Physician's Weekly

Atrial fibrillation emerged as a frequent and potentially prognostic complication in wild-type transthyretin amyloidosis, driven by distinct clinical risk factors. A study published in June 2025 issue of American Journal of Cardiology underscored the frequent occurrence of atrial fibrillation (AF) in wild-type transthyretin amyloidosis (ATTRwt) and the limited understanding of its timing, risk factors, and clinical outcomes.

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Metabolic Outcomes in Relatives of Women With PCOS

Physician's Weekly

First-degree relatives of women with PCOS showed significantly higher rates of metabolic disorders, revealing a familial cardiometabolic burden. Researchers conducted a retrospective study published in June 2025 issue of Clinical Endocrinology to examine the cardiometabolic health of first-degree relatives (FDR) of individuals with polycystic ovary syndrome (PCOS).

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Tracking Structural Decline in MAK-Associated Retinopathy

Physician's Weekly

Progressive retinal layer thinning in MAK-RP highlights the need for alternative markers to monitor preserved central vision over time. Researchers conducted a retrospective study published In June 2025 issue of American Journal of Ophthalmology to describe the clinical features and disease progression patterns in individuals with Male Germ Cell-Associated Kinase (MAK)-associated retinitis pigmentosa (MAKRP).

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Sedentary Patterns and Clinical Factors Predict Diabetes Risk

Physician's Weekly

A predictive model using sedentary behavior and simple clinical data accurately identified office workers at risk for type 2 diabetes mellitus. A study published in June 2025 issue of Primary Care Diabetes reported that sedentary behavior (SB) is a major risk factor contributing to the high prevalence and underdiagnosis of type 2 diabetes mellitus (DM2).

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Long-Term Cancer Rates Stable After TB in HIV

Physician's Weekly

A nationwide study found that TB history did not elevate long-term cancer risk among individuals living with HIV. Researchers conducted a retrospective study published in June 2025 issue of Journal of Infectious Diseases to evaluate long-term cancer risk after TB in a cohort of individuals with HIV in Denmark. They used data from the Danish HIV Cohort Study between 1995 and 2020; TB and cancer diagnoses were identified through national registries.

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Differential Cardiovascular Shifts in Treated PD

Physician's Weekly

Multimodal therapy revealed sex-specific cardiovascular shifts in Parkinson’s disease. A study published in June 2025 issue of BMC Neurology explored sex-based differences in cardiovascular dysregulation (CDR) among individuals with Parkinson’s disease (PD), highlighting the potential role of heart rate (HR) variability and electrodermal activity (meanEDA) in understanding autonomic changes during therapy.

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Medication Abortion Outcomes by Screening Status

Physician's Weekly

Eliminating routine screenings in medication abortion care proved safe and effective, offering a path to reduce delays and expand reproductive autonomy. A study published in the June 2025 issue of American Journal of Obstetrics & Gynecology examined changes in clinician practices during COVID-19, revealing that despite strong evidence supporting streamlined “no-test” medication abortion to improve access, in-person protocols remain prevalent.