Sat.Jun 28, 2025

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Why public health must be included in AI development

KevinMD

When artificial intelligence developers gather to build tools that will reshape health care, one critical voice is often missing: public health. Despite AI’s potential to improve outcomes and streamline operations, it is being developed with limited regard for public health priorities. The absence of this input is not just a technical oversight.

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Molecular Subtypes and Surgical Approaches in Endometrial Cancer

Physician's Weekly

Personalized care may hold the key as survival in advanced endometrial cancer remains poor regardless of surgery type or tumor subtype. Researchers conducted a retrospective study published in the June 2025 issue of European Journal of Obstetrics and Gynecology and Reproductive Biology to examine oncologic outcomes and prognostic factors across molecular subtypes of advanced or metastatic endometrial cancer treated with primary debulking surgery (PDS) or neoadjuvant chemotherapy (NACT) followe

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Generative AI 2025: a 20-minute cheat sheet for busy clinicians

KevinMD

Why doctors should care Generative AI has moved from hype to bedside utility. Ambient “copilot” apps draft encounter notes. Large language models (LLMs) summarise new studies in seconds. Early adopters save hours each week and report less burnout. Five core concepts, clinical parallels Neural networks → Repeated pattern-finding, like residents running endless simulations.

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Persistent Neurological Symptoms After COVID-19

Physician's Weekly

Widespread post-COVID neurological symptoms reveal hidden long-term impacts, calling for a proactive clinical response. Researchers conducted a retrospective study published in the June 2025 issue of BMC Neurology to evaluate the long-term neurological effects on adults with COVID-19 and to inform future mental health service planning. They performed a comprehensive literature search across 5 electronic databases—PubMed, Scopus, Web of Science, EBSCO, and CENTRAL—covering publications up t

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Why are medical students turning away from primary care? [PODCAST]

KevinMD

Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes! Medical students Vineeth Amba and Archita Goyal discuss their article, “What’s driving medical students away from primary care?” They share the widespread discouragement medical students encounter regarding primary care careers, despite initial aspirations to serve communities.

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Comparing Long-Term Pressure Outcomes in Glaucoma Surgery

Physician's Weekly

Trabeculectomy showed stronger long-term pressure control, while canaloplasty offered a safer profile with fewer complications. An 11-year cohort study published in June 2025 in the issue of BMC Ophthalmology evaluated the long-term outcomes of trabeculectomy versus canaloplasty (TVC) in individuals with open-angle glaucoma. They followed individuals from the original 2015 TVC cohort.

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International doctors blocked by visa delays as U.S. faces physician shortage

KevinMD

This story is fiction but inspired by the real and worsening challenges faced by international medical graduates navigating U.S. immigration policy. The acceptance letter sat printed on top of Nabeel Khan’s passport, still warm from the old inkjet printer in his family’s living room in Lahore. The words glowed like prophecy: “Congratulations!

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Why “do no harm” might be harming modern medicine

KevinMD

Recently, while reading The History of Medicine by William Bynum, I was struck by a line that quietly reframed a great deal of what we claim to believe about our profession. Reflecting on how medicine has evolved, Bynum writes: “When in doubt, remember the Hippocratic injunction that health is most likely to be found in the Read more… Why “do no harm” might be harming modern medicine originally appeared in KevinMD.com.

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Diagnostic Accuracy of PCT in Stroke-Related Pneumonia

Physician's Weekly

Procalcitonin emerged as a strong diagnostic marker that may boost early SAP detection when combined with predictive models. A study published in June 2025 issue of BMC Pulmonary Medicine highlighted the importance of early biomarker identification and predictive modeling to address the burden of stroke-associated pneumonia (SAP) on recovery and outcomes.

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A world without vaccines: What history teaches us about public health

KevinMD

What would a world without vaccines even look like? Well, it turns out that we don’t have to wonder since accurate historical records allow us to distinctly see and learn for ourselves. This is in keeping with our Secretary of Health and Human Services’ (HHS) recent guidance to Do Your Own Research. What we actually Read more… A world without vaccines: What history teaches us about public health originally appeared in KevinMD.com.

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Tyrosine Kinase Modulation in Skin Rejuvenation

Physician's Weekly

Enzyme-targeted modulation offers novel promise for enhancing skin tone and texture. A study published in June 2025 issue of Frontiers in Medicine highlighted the critical role of tyrosine kinases (TKs) in regulating key cellular processes involved in dermatologic conditions. Researchers explored how TKs influenced pigmentation, aging , and inflammation in dermatologic conditions, aiming to clarify their underlying mechanisms and therapeutic relevance.

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J.M. Smucker plans to remove artificial colors from its jams and other products

NPR Health

Smucker joins a growing number of big food companies that have announced plans to eliminate artificial dyes.

IT 58
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Referral Patterns and Gaps in HLA-B27

Physician's Weekly

Testing for the HLA-B27 allele showed widespread use across specialties and revealed missed opportunities for rheumatology referrals in positive cases. A retrospective analysis study published in June 2025 issue of Journal of Rheumatology, researchers examined how HLA-B27 testing has been utilized in routine clinical practice for diagnosing spondylarthritis ( SpA ).

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'Where's our money?' CDC grant funding is moving so slowly layoffs are happening

NPR Health

The state and local health departments that rely on CDC funding say the money is not coming in on time and no one can tell them why. Some are laying off staff.

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Insurance-Based Variation in Repeat mt-sDNA Test Adherence

Physician's Weekly

High adherence to repeat mt-sDNA testing highlighted disparities driven by insurance type and before-screening history. Researchers conducted a study published in June 2025 issue of the Journal of Primary Care & Community Health to assess repeat mt- sDNA screening adherence among individuals from federally qualified health centers (FQHCs) across the US by payer type , as part of ongoing efforts to improve colorectal cancer screening.

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Hard to imagine a worse time to deport Afghan refugees, human rights advocates say

NPR Health

There were 71,000 deportations in the first half of June alone, according to U.N. estimates. These Afghan refugees are returning to a country in the throes of a humanitarian crisis.

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Evidence Appraisal of Publication Bias in Hypospadias Trials

Physician's Weekly

Hypospadias surgery trials show minimal publication bias, supporting the reliability of current research. In a study published in June 2025 in the issue of International Journal of Urology, Researchers assessed publication bias in hypospadias research and its potential influence on clinical decision-making. They performed a literature review across 4 public databases to identify peer-reviewed randomized controlled trials (RCTs) assessing surgical approaches for hypospadias, focusing on succ

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Racial Gaps in Preventive Breast Surgery Uptake

Physician's Weekly

People from different racial and ethnic backgrounds showed varied uptake of preventive mastectomy among those with genetic breast cancer risk. A study published in June 2025 issue of American Journal of Surgery , researchers compared the rates of risk-reducing mastectomi es (RRM) among individuals with breast cancer (BC) –related pathogenic variants.

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Enhanced Ventricular-Arterial Coupling With S/V Therapy

Physician's Weekly

Improved heart function with sacubitril/valsartan was linked to enhanced ventricular-arterial coupling and cardiac efficiency in individuals with reduced ejection fraction. A study published in June 2025 issue of American Journal of Cardiology described left ventricular (LV) reverse remodeling (RR) as a known response to therapies that alleviate neurohormonal activation and hemodynamic overload in individuals with heart failure with reduced ejection fraction (HFrEF).

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Diminished Plasma Volume With Repeat Crystalloid Bolus

Physician's Weekly

Repeated crystalloid boluses led to progressively weaker plasma volume expansion. Researchers conducted a retrospective study published in June 2025 issue of Annals of Intensive Care to evaluate whether repeated bolus infusions of crystalloid and colloid fluids produced consistent increases in plasma volume to support the assumptions of goal-directed fluid therapy.

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Utility of HANDOC and CH-A in Endocarditis Triage

Physician's Weekly

Risk scoring tools like HANDOC and CH-A improved infective endocarditis detection in NBHS bloodstream infections but increased transesophageal echocardiography use. In a study published in the June 2025 issue of Infectious Disease, non-β-hemolytic streptococci (NBHS) were identified as important causes of blood stream infections (BSI) , which were often complicated by infective endocarditis (IE), prompting interest in risk stratification tools to support clinical decision-making.

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Altered Pain Processing in Knee Osteoarthritis

Physician's Weekly

Central pain dysregulation in knee osteoarthritis reveals the need for treatments targeting both peripheral and nociplastic mechanisms. Researchers conducted a study published in June 2025 in the issue of the Journal of Pain to evaluate existing evidence on conditioned pain modulation (CPM) and temporal summation of pain (TSP) in individuals with knee osteoarthritis (KOA) compared to pain-free controls.

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Pirtobrutinib Enhances Disease Control in Relapsed CLL/SLL

Physician's Weekly

Targeted BTK inhibition with pirtobrutinib offers durable disease control and improved safety in relapsed CLL/SLL. In a Phase III Trial study published in June 2025 issue of Journal of Clinical Oncology, researchers compared the efficacy and safety of pirtobrutinib vs investigator’s choice (IC) of idelalisib/rituximab (IdelaR) or bendamustine/rituximab (BR) in patients with R/R chronic lymphocytic leukemia or small lymphocytic lymphoma (SLL) previously treated with covalent Bruton tyrosine kinas

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Post-Transplant Survival and Immunosuppressive Trends

Physician's Weekly

Shifting immunosuppressive trends in France revealed strong kidney transplant survival and a steady reliance on calcineurin inhibitors from 2009 to 2020. Researchers conducted a retrospective study published in the May 2025 issue of Journal of Nephrology to describe immunosuppressive medication use and survival outcomes in patients who underwent kidney transplantation in France between 2009 and 2020.

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Hormonal and Clinical Factors Linked to Microscopic Colitis

Physician's Weekly

Microscopic colitis progression showed links with smoking, celiac disease, and a potential protective role of bilateral oophorectomy. A study published in June 2025 issue of BMC Gastroenterology on microscopic colitis (MC) was marked by non-bloody, watery diarrhea, primarily affecting older women, with limited data available on hormonal risk factors.

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Physician Views on Certifying Assisted Dying

Physician's Weekly

Swedish doctors navigated ethical uncertainty yet largely endorsed aiding assisted dying abroad through medical certification to support patient autonomy. A research study published in June 2025 issue of Frontiers in Psychiatry explored the ethical and professional uncertainties faced by Swedish physicians due to the lack of clear guidelines for supporting patients requesting medical certificates.

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Racial and Age Gaps in Teen Firearm Injuries

Physician's Weekly

Firearm injuries surged among King County teens, hitting hardest among older males and marginalized groups, underscoring urgent local prevention needs. Researchers conducted a retrospective study published in June 2025 in the issue of BMC Pediatrics to examine adolescent firearm injury trends using localized data to uncover disparities masked by national statistics.

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