Sun.Jul 06, 2025

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Why testosterone matters more than you think in women’s health

KevinMD

Menopause is finally having its moment in the spotlight, thanks to high-profile women breaking the long-standing taboo around discussing this life stage. Yet, while discussions around hormone replacement therapy (HRT) have increased, one critical component remains largely overlooked — testosterone. Traditionally seen as a “male hormone,” testosterone is equally vital for women’s health, playing a Read more… Why testosterone matters more than you think in women’s health or

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Staying In the Practice of Medicine.

Mere Mortal MD

In January of 2023 I went on a life altering retreat to Costa Rica. The night I signed up was a snap decision, born out of a traumatic event that happened in my workplace. My fight or flight was still rearing its ugly head until well after midnight, so I stopped trying to go to sleep and pulled out my laptop. I was trying to just fill time until I got sleepy and was going through my emails when I landed on one advertising a retreat to Costa Rica.

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A mind to guide the machine: Why physicians must help shape artificial intelligence in medicine

KevinMD

I do not fear artificial intelligence—nor do I revere it. What I feel toward the rise of intelligent systems in medicine is something quieter: a tempered trust, a measured hope. I recognize their immense potential, but I also hold firm to the belief that the deepest work of medicine happens not through automation, but through Read more… A mind to guide the machine: Why physicians must help shape artificial intelligence in medicine originally appeared in KevinMD.com.

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Strategic Consensus to Improve Access to Home Dialysis

Physician's Weekly

A multi-stakeholder forum outlined practical, community-driven solutions to overcome disparities and expand the use of Home Dialysis across Europe. Researchers conducted a retrospective study published in June 2025 issue of BMC Nephrology to evaluate the underuse and variability of home dialysis across Europe and to identify modifiable barriers contributing to inequitable access.

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How to Start Virtual Care the Right Way: A Proven Roadmap for 2025 and Beyond

Speaker: Dr. Christine Gall, DrPH, MS, BSN, RN

The promise of virtual care is no longer theoretical and is now a critical solution to many of healthcare’s most urgent challenges. Yet many healthcare leaders remain unsure how to build a business case for investment and launching the right program at the right time can be the difference between value and failure. For organizations seeking a financially sound, clinically effective entry point, Virtual Patient Observation (VPO) offers a compelling case to lead with.

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The emotional first responders of aesthetic medicine

KevinMD

When people think of Botox and filler, they think of vanity. Frozen foreheads. Pouty lips. Women chasing youth. Injectors chasing cash. They don’t see the woman who finally escaped her husband after 20 years of abuse, coming in not for attention but for control. They don’t see the mother burying her child, hoping that looking Read more… The emotional first responders of aesthetic medicine originally appeared in KevinMD.com.

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Machine Learning for Candidemia Detection in Sepsis

Physician's Weekly

Deep learning using routine lab data showed promise in distinguishing candidemia from bacteremia but fell short of outperforming established biomarkers. Researchers conducted a retrospective study published in June 2025 issue of Infectious Diseases and Therapy to assess the impact of early diagnosis on outcomes in individuals with candidemia, bloodstream infection (BSI) particularly those presenting with septic shock.

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Neuroimaging Insights Into Risperidone Effects in Schizophrenia

Physician's Weekly

Risperidone alters key brain regions in schizophrenia, with future imaging tools offering insights into its long-term effects and neural mechanisms. A study published in June 2025 issue of Frontiers in Psychiatry explored how risperidone influences brain function and symptom improvement in schizophrenia (SZ) using advanced magnetic resonance imaging (MRI) techniques.

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How President Biden’s cognitive health shapes political and legal trust

KevinMD

In the realm of American politics, discussing the mental fitness of a sitting president – or the performance of a former one – is as delicate as it is critical. As a psychiatrist, I am profoundly aware of the ethical constraints outlined by the Goldwater Rule, adopted by the American Psychiatric Association (of which I Read more… How President Biden’s cognitive health shapes political and legal trust originally appeared in KevinMD.com.

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Panel-Based RPM Intervention Reduced Blood Pressure

Physician's Weekly

A tailored RPM approach using panel management led to high engagement and significant blood pressure reductions across primary care settings. Researchers conducted a retrospective study published in July 2025 issue of BMC Primary Care to examine implementation strategies and clinical outcomes of the multi-component Remote patient management (RPM) intervention ‘Connect@Heart’ for cardiovascular risk management.

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When it comes to vaccines, how are pediatricians restoring trust?

NPR Health

If you're a parent, decisions about vaccines have gotten a lot more confusing recently. Robert F. Kennedy, Jr.'s health department is walking back longstanding recommendations. NPR's Pien Huang speaks with a pediatrician and a vaccine researcher to discuss how the changes may affect public health - and how frontline conversations are going between pediatricians and families.

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Strain-Sensitive Thermochromic Smart Electronic Skin for Joint and Spine Healthcare Applications.

Physician's Weekly

Electronic skins (E-skins) that enable interactive and quantitative joint and spine healthcare hold transformative potential for personalized musculoskeletal rehabilitation. However, existing systems face three critical limitations: conventional strain sensors degrade with cyclic large strain due to uncontrolled crack propagation; thermal therapy lacks real-time adaptive control without feedback; and systems lack user-interactive monitoring-therapy integration.

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A new report offers insights for U.K. efforts to improve polluted water supply

NPR Health

A new report offers insights for U.K. efforts to improve areas with polluted water supplies.

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Efficacy and safety of GLP-1 agonists in the treatment of T2DM: A systematic review and network meta-analysis.

Physician's Weekly

To compare efficacy and safety of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in subjects with type 2 diabetes (T2DM). Electronic databases were searched from inception to 2nd October 2024 for randomised controlled trials comparing GLP-1RAs treating T2DM. Bayesian network meta-analyses were conducted to analyze metabolic and safety outcomes. 64 trials comprising of 25,572 participants were identified.

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4 things to know about the vaccine ingredient thimerosal

NPR Health

Advisers to the Centers for Disease Control and Prevention recommended against flu shots containing the ingredient thimerosal. Why is the additive, safely used since the 1930s, being questioned again? (Image credit: Marie D.

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Reduced Toxicity and Better Survival With N-AVD in cHL

Physician's Weekly

Nivolumab-AVD outperforms BV-AVD in efficacy and safety, offering a promising frontline option for OAs with advanced classic Hodgkin lymphoma. Researchers conducted a retrospective study published in June 2025 issue of Journal of Clinical Oncology to compare survival outcomes between older and younger individuals diagnosed with classic Hodgkin lymphoma (cHL).

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Valve Positioning Strategy Lowers PPI After TAVR 

Physician's Weekly

Cusp overlap view improved valve positioning and significantly reduced pacemaker need, and hospital stay in TAVR with SEVs. Researchers conducted a retrospective study published in June 2025 issue of American Journal of Cardiology to compare the cusp overlap view (COV) technique with the conventional coplanar view in transcatheter aortic valve replacement (TAVR) using self-expanding valves (SEVs), focusing on conduction outcomes and implantation characteristics.

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Healing Benefits of GFs in Diabetic Foot Care

Physician's Weekly

Growth factors like epidermal and platelet-derived types showed strong benefits in accelerating healing and reducing complications in DFUs. Researchers conducted a retrospective study published in June 2025 issue of Frontiers in Endocrinology to compare the efficacy and safety of various growth factors (GFs) in treating diabetic foot ulcers (DFUs) u`sing a network meta-analysis.

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High proportion of depression and anxiety in younger patients with COPD: a cross-sectional study in primary care in Sweden.

Physician's Weekly

Patients with COPD and concurrent depression and/or anxiety are known to have an increased risk of exacerbations, morbidity, mortality, and deteriorated quality of life. Early detection of depression/anxiety may enable early interventions. The aims of this study were to describe the occurrence of depression and anxiety in primary care patients with COPD in Sweden, and to investigate age and gender differences together with other clinical factors associated with this comorbidity.

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Perceptions of COPD Exacerbations and Communication Gaps

Physician's Weekly

Many individuals with chronic obstructive pulmonary disease describe exacerbations in personal, varied terms, revealing a need for clearer, patient-centered communication in care. Researchers conducted a retrospective study published in June 2025 issue of International Journal of Chronic Obstructive Pulmonary Disease to explore how individuals living with chronic obstructive pulmonary disease (COPD) perceived and communicated their experiences of exacerbations.

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Impact of RoSCo-based preoperative risk stratification on early mobilization and short-term outcomes following robot-assisted laparoscopic partial nephrectomy for renal cell carcinoma: a single-center prospective study.

Physician's Weekly

This study aimed to evaluate the effectiveness of the RoSCo preoperative risk scoring system, which incorporates the RENAL Nephrometry Score, the Charlson’s Comorbidity Index, and body mass index to quantify surgical risk, in guiding individualized early mobilization protocols and to assess associated early postoperative recovery outcomes in patients undergoing robot-assisted partial nephrectomy (RAPN) for renal cell carcinoma (RCC).

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Comparing traditional natural language processing and large language models for mental health status classification: a multi-model evaluation.

Physician's Weekly

The substantial increase in mental health disorders globally necessitates scalable, accurate tools for detecting and classifying these conditions in digital environments. This study addresses the critical challenge of automated mental health classification by comparing three distinct computational approaches: (1) Traditional Natural Language Processing (NLP) with advanced feature engineering, (2) Prompt-engineered large language models (LLMs), and (3) Fine-tuned LLMs.

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Clinical Benefit of Pivmecillinam for uUTIs

Physician's Weekly

Pivmecillinam proved highly effective in treating uUTIs, with trial reanalysis supporting its FDA approval after decades of European use. Researchers conducted a retrospective study published in June 2025 issue of Clinical Infectious Diseases to reanalyze data from earlier clinical trials using current Food and Drug Administration (FDA) efficacy criteria to support the approval of pivmecillinam for uncomplicated urinary tract infection (uUTI).

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Unveiling Quality of Life Factors for the Elderly: A Public Health Nursing Approach Enhanced by Advanced ML and DL Techniques.

Physician's Weekly

Community health nurses can enhance the elderly’s quality of life (QoL) through personalized care, lifestyle counselling, and preventive measures. The primary objective of this study was to develop artificial intelligence (AI)-based prediction models to identify the key influencing factors that can impact the QoL in the elderly population. The estimated sample size was 500, and participants were selected using a systematic sampling technique.

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Smoking and Stress Worsen Menopause in Working Women

Physician's Weekly

Understanding the link between job strain, stress, and smoking to severe climacteric symptoms, urging better workplace and healthcare support for midlife women. Researchers conducted a retrospective study published in the July 2025 issue of European Journal of Obstetrics and Gynecology and Reproductive Biology to explore how work- and health-related factors were associated with climacteric symptoms among middle-aged full-time working women prior to receiving any treatment.

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Treatment Response Patterns to Biologics in Plaque Psoriasis

Physician's Weekly

Early biologic response patterns in plaque psoriasis revealed faster remission with anti-IL-17AF and underscored the need for tailored treatment strategies. A study published in June 2025 issue of Clinical, Cosmetic and Investigational Dermatology described how biologic therapies have reshaped the management of moderate to severe psoriasis (PsO) in Poland through the National Health Service’s B.47 program, implemented since 2013.

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Bayesian Mortality Analysis in Older Adults

Physician's Weekly

Slightly elevated mortality in nonagenarians highlights the need for individualized ICU care guided by more than age. Researchers conducted a retrospective study published in June 2025 issue of Annals of Intensive Care to evaluate outcomes and prognostic uncertainty in individuals aged 90 years or older (nonagenarians) admitted to intensive care units (ICUs).

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Association of Social Isolation With Type 2 Diabetes Risk

Physician's Weekly

Social disconnection emerged as a potential driver of type 2 diabetes, revealing the hidden metabolic cost of loneliness and isolation. Researchers conducted a retrospective study published in June 2025 issue of Primary Care Diabetes to examine the relationship between social isolation, loneliness, and the incidence risk of type 2 diabetes mellitus (T2DM).

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Transcriptomic and Neurotransmitter Insights Into Gray Matter Volume Changes From 1 Hz rTMS in Treating Schizophrenia With Auditory Verbal Hallucinations.

Physician's Weekly

Auditory verbal hallucinations (AVH) are prominent positive symptoms of schizophrenia that frequently prove resistant to conventional antipsychotic treatments. Low-frequency repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising intervention for AVH; however, the underlying neurobiological mechanisms mediating its efficacy remain incompletely understood.

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Survey of medical student attitudes regarding uterine transplant for cisgender and transgender women: an observational study.

Physician's Weekly

This study wishes to survey medical students’ attitudes regarding legality of, funding for, and conscientious objection to uterine transplant (UTx) in cisgender and transgender women. Medical students were invited to complete an online anonymous survey from March 18, 2024 to April 1, 2024. Baseline demographics collected, and four-point Likert scales were used on four pairs of questions to evaluate attitudes regarding UTx for cisgender and transgender women.

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Survival Gaps in Lung and Pancreatic Cancer

Physician's Weekly

Medicare Advantage enrollment was linked to poorer cancer survival despite similar adherence to treatment guidelines. A study published in June 2025 issue of Annals of Surgery explored how cancer care and outcomes may differ between individuals enrolled in Medicare Advantage (MA) and those enrolled in Traditional Medicare (TM). Researchers conducted a retrospective study to examine the impact of Medicare insurance status on the quality of care and survival outcomes in individuals diagnose

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Prognostic Role of Frailty in Nonaneurysmal SAH

Physician's Weekly

Pre-existing frailty strongly predicted poor recovery at 6 months after nonaneurysmal subarachnoid hemorrhage. Researchers conducted a retrospective study published in July 2025 issue of Journal of Neurology to examine the link between pre-existing frailty and functional outcomes in individuals with spontaneous, nonaneurysmal subarachnoid hemorrhage (naSAH) who exhibited a normal cerebral angiogram during evaluation of the bleeding source.

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Chimerism and GVHD Shape Survival Post-Transplant DLI

Physician's Weekly

Achieving donor chimerism or GVHD after infusion boosted survival only in relapse cases without prior GVHD, revealing a key window for GVL benefit. Researchers conducted a retrospective study published in June 2025 issue of British Journal of Haematology to examine whether prior graft-versus-host disease (GVHD) influenced the impact of donor lymphocyte infusion (DLI) on full donor chimerism (FDC) and subsequent GVHD after allogeneic stem cell transplantation (alloHSCT) relapse.

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Glaucoma Medication Use After Combined Procedures

Physician's Weekly

Modest medication reduction was sustained postoperatively in both surgical groups, highlighting comparable long-term benefits. Researchers conducted a retrospective study published in June 2025 issue of Clinical Ophthalmology to compare postoperative outcomes in individuals who underwent cataract surgery with OMNI canaloplasty and Hydrus Microstent implantation vs those who received cataract surgery with OMNI canaloplasty alone.

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Ceramide Ratio Linked to Severity in IBD and PSC

Physician's Weekly

Elevated long-chain to very long-chain ceramide ratios emerged as potential biomarkers linked to disease severity across IBD, PSC, and PSC-IBD. A study published in June 2025 issue of Scientific Reports explored the distinct roles of circulating ceramide (Cer) species and their unclear links to disease severity in individuals with inflammatory bowel disease (IBD) and primary sclerosing cholangitis (PSC).

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Adaptive Antioxidant Nanomedicines Inhibit Ferroptosis in Renal Tubular Epithelial Cells to Alleviate Diabetic Kidney Disease.

Physician's Weekly

Diabetic kidney disease (DKD) imposes a heavy medical burden worldwide due to the lack of effective treatment. High levels of mtROS and mitochondrial damage in the renal tubules are the initiating and core factors driving the progression of DKD. However, the effectiveness of current antioxidant drugs is greatly limited, mainly due to the difficulty of simultaneously breaching the glomerular barrier and targeting tubular mitochondria, as well as their limited ability to sustain treatment of chron

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Aligned Conductive Magnetic Nanofibers with Directional Magnetic Field Stimulation Promotes Peripheral Nerve Regeneration.

Physician's Weekly

Peripheral nerve injury is one of the most common disorders of the nervous system. Alternatives to autologous nerve transplantation have attracted significant interest among researchers. In this study, magnetic nanoparticles are integrated with oriented polycaprolactone (PCL) fibers, followed by the addition of a polypyrrole (Ppy) coating. Ppy-PCL/FeO, when combined with a static magnetic field, activates the superparamagnetic properties of the nanoparticles while ensuring conductivity, creating

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