Sat.Jun 14, 2025

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Why health care must adapt to meet the needs of older adults with disabilities

KevinMD

We all know the population is aging, but did you know that close to half of all adults over age 65 in the U.S. have some kind of disability? The Americans with Disabilities Act (ADA) includes as a disability any “physical or mental impairment that limits one or more life activities” or a history or Read more… Why health care must adapt to meet the needs of older adults with disabilities originally appeared in KevinMD.com.

Physicals 306
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Comparing Vancomycin Dosing Strategies in Cystic Fibrosis

Physician's Weekly

The following is a summary of ā€œVancomycin Monitoring for Treatment of Acute Pulmonary Exacerbations of Adult Cystic Fibrosis Patients,ā€ published in the May 2025 issue of Pulmonary Medicine by Smith et al. Researchers conducted a retrospective study to compare vancomycin (VAN) trough and area under the curve (AUC) monitoring for reducing acute kidney injury (AKI) risk in adult people with cystic fibrosis.

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Earwax could hold secrets to cancer, Alzheimer’s, and heart disease

KevinMD

Most of us think of earwax as a nuisance–something to be cleaned out and discarded. But, did you know that this sticky substance is a natural part of your body that can reveal information about your health? If you regularly clean your ears at home, it’s worth a second thought. Although a part of general Read more… Earwax could hold secrets to cancer, Alzheimer’s, and heart disease originally appeared in KevinMD.com.

IT 269
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Nasal Inflammatory Gene Profiles Linked to COVID

Physician's Weekly

The following is a summary of ā€œTowards precision medicine: inflammatory nasal epithelial transcriptomic profiles in long COVID,ā€ published in the June 2025 issue of Journal of Allergy and Clinical Immunology by Baalbaki et al. Researchers conducted a retrospective study to examine nasal epithelial transcriptomes in individuals with long COVID (LC) to explore underlying pathophysiological mechanisms for disease management.

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How doctors took back control from hospital executives

KevinMD

Several decades ago at our local hospital in northern Los Angeles County, an onslaught against doctors began. The administration marginalized and discredited them. It was not due to a lack of medical skill or knowledge, as certain physicians were labeled “troublemakers” and “threats” to health care in our small community. The chief of staff and Read more… How doctors took back control from hospital executives originally appeared in KevinMD.com.

Hospital 167
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Organ Use and Transplant Access by Center Volume

Physician's Weekly

The following is a summary of ā€œBeing Waitlisted is not Enough—Identification of Pseudo-access to Kidney Transplantation in the United States,ā€ published in the May 2025 issue of Annals of Surgery by Matevish et al. Researchers conducted a retrospective study to examine how transplant center volume influenced access to kidney transplants among waitlisted candidates.

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Inside human trafficking: a guide to recognizing and preventing it [PODCAST]

KevinMD

Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes! Public policy analyst Julia Drydyk discusses her article “Human trafficking isn’t what you think: Why education is key to stopping it.” Julia clarifies the crucial distinction between human smuggling and human trafficking, explaining that trafficking involves exploitation through coercion regardless of Read more… Inside human trafficking: a guide to recognizing and preventing it [PODCAST] originall

IT 219

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Why male fertility needs to be part of every health conversation

KevinMD

June is Men’s Health Month, an opportunity to spotlight the unique health challenges men face—and to change the way we talk about them. One of the most overlooked and under-discussed topics in men’s health? Fertility. It’s time to bring it to the forefront. As a fellowship-trained urologist specializing in sexual medicine and male fertility, I’ve Read more… Why male fertility needs to be part of every health conversation originally appeared in KevinMD.com.

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Tuberculosis Patterns Vary by Migrant Origin and Arrival Timing

Physician's Weekly

The following is a summary of ā€œDifferences found in patient characteristics of migrant tuberculosis sub-populations within low TB incidence European countries, 2014–2020,ā€ published in the June 2025 issue of BMC Infectious Diseases by Jackson et al. Efforts in low TB incidence countries to control tuberculosis (TB) historically underlined prevention and care for migrant populations, as understanding their characteristics was crucial for effective planning and provision of appropriate care.

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Ancient miasma theory may help explain Health Secretary Robert F. Kennedy Jr.'s vaccine moves

NPR Health

Health Secretary Robert F. Kennedy Jr. apparently embraces the outdated "miasma theory" of disease instead of the widely accept "germ theory" of disease, which may help explain some of the actions he's been taking.

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Trial of a Strategy to Reduce Antidepressants in Dementia

Physician's Weekly

The following is a summary of ā€œEffects of deprescribing antidepressants in nursing home residents with dementia—a cluster randomized controlled trial,ā€ published in the June 2025 issue of BMC Primary Care by HĆølmkjƦr et al. Antidepressants were frequently prescribed to older nursing home residents with dementia, a neurological disorder, despite limited clinical benefit and substantial risk of side effects.

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Doing Cancer Wrong

Adventures of a Sick Doctor

For whatever reason, I never seem to cop on to the right ways of doing things - socially I mean - especially if there isn’t a written set of instructions. I have an innate tendency to do precisely the opposite of what society expects from me. If I am supposed to smile and be sweet, I scowl and swear. If I am supposed to frown and shake my head, I tip my head back and laugh.

Family 162
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Risk Factors for Coercion in Open Psychiatric Inpatient Wards

Physician's Weekly

The following is a summary of ā€œPrevalence and risk factors for seclusion and restraint: results of a retrospective analysis,ā€ published in the June 2025 issue of BMC Psychiatry by Wullschleger et al. The reduction of coercion was a major challenge in inpatient mental health services, with limited knowledge about seclusion and restraint use in open-door settings.

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Natural History of Asymptomatic Renal Stones Before RC

Physician's Weekly

The following is a summary of ā€œDoes having an asymptomatic renal stone increase morbidity after radical cystectomy?,ā€ published in the May 2025 issue of World Journal of Urology by Savin et al. Asymptomatic renal stones detected before radical cystectomy (RC) and urinary diversion (UD) presented a potential treatment challenge. Researchers conducted a retrospective study to examine the outcomes and natural history of asymptomatic renal stones managed by observation following RC and UD.

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Triglyceride-Glucose Indices Predict Risk of NASH in NAFLD

Physician's Weekly

The following is a summary of ā€œAssociation between triglyceride-glucose related indices and at-risk NASH in U.S. adults with NAFLD: results from NHANES 2017-2020,ā€ published in the June 2025 issue of Frontiers in Endocrinology by Ma et al. Nonalcoholic fatty liver disease (NAFLD) has been closely associated with insulin resistance (IR), obesity , and metabolic syndrome (MetS), affecting a significant portion of the global population.

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Fellowship Training Enhances Physician-Led Laser Dermatology Care

Physician's Weekly

The following is a summary of ā€œCosmetic Lasers in the US: Who’s Using Them, the Latest Technology, and What Patients Need to Know,ā€ published in the May 2025 issue of Journal of Cosmetic Dermatology by Coyle and Kesty. The use of laser treatments for cosmetic and medical dermatologic conditions had increased, while provider training varied widely, raising concerns about patient safety and treatment effectiveness.

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Declining Uveitic Glaucoma Incidence and Subtype Risks

Physician's Weekly

The following is a summary of ā€œIncidence and Prevalence of Glaucoma, Corticosteroid Response, and Ocular Hypertension in Uveitis and its Anatomical Subtypes,ā€ published in the June 2025 issue of American Journal of Ophthalmology by Marshall et al. Researchers conducted a retrospective study to evaluate the cumulative and annual prevalence and incidence of uveitic glaucoma within the TriNetX United States (US) Collaborative Network database.

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Lung Function Differences in Congenital Defects

Physician's Weekly

The following is a summary of ā€œLong-Term Pulmonary Function Outcomes in Children with Pulmonary Hypoplasia,ā€ published in the May 2025 issue of Journal of Pediatrics by Gipsman et al. Researchers conducted a retrospective study to examine whether the cause of pulmonary hypoplasia influenced lung growth trajectories by assessing pulmonary function in children aged 8 to 13 years born with congenital diaphragmatic hernia (CDH), early intervention congenital lung malformation (EICLM), and giant o

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World Blood Donor Day 2025 Arrives as Summer Blood Supplies Often Run Low

Physician's Weekly

According to the World Health Organization, WHO, World Blood Donor Day is celebrated on June 14 annually and honors the selfless act of voluntary blood donors whose contributions save lives and embody global solidarity. 1 This year’s campaign emphasizes the hope blood donations bring to millions of patients worldwide. Key goals include: raising awareness of the ongoing need for blood and plasma; encouraging regular donations; highlighting donors’ life-saving impact; and urging government a

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Trial of Pembrolizumab and Enzalutamide in mCRPC

Physician's Weekly

The following is a summary of ā€œPembrolizumab plus enzalutamide versus placebo plus enzalutamide for chemotherapy-naive metastatic castration-resistant prostate cancer: the randomized, double-blind, phase III KEYNOTE-641 study,ā€ published in the May 2025 issue of Annals of Oncology by Graff et al. Patients with metastatic castration-resistant prostate cancer (mCRPC), established first- and second-line standard-of-care treatments, including abiraterone, enzalutamide, and taxane chemotherapy, wer

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Altered Cerebellar Network in Dystonia

Physician's Weekly

The following is a summary of ā€œStructure–function association of the cerebellar motor network is altered in isolated cervical dystonia,ā€ published in the June 2025 issue of Journal of Neurology by Grimm et al. Cervical dystonia (CD) was identified as a disorder involving the brain’s sensorimotor network, with the cerebellum playing a key but not fully understood role.

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Deep Learning for Predicting MAKE30 in AKI

Physician's Weekly

The following is a summary of ā€œORAKLE: Optimal Risk prediction for mAke30 in patients with sepsis associated AKI using deep LEarning,ā€ published in the May 2025 issue of Critical Care by Oh et al. Major Adverse Kidney Events within 30 days (MAKE30) were recognized as a key patient-centered outcome for evaluating acute kidney injury (AKI), while existing prediction models remained static and failed to capture dynamic clinical changes.

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Clinical Validity of PLASMIC Score in aHUS Identification

Physician's Weekly

The following is a summary of ā€œPLASMIC score to aid diagnosis of aHUS: an analysis of C5 inhibitor clinical trials and the PINC AIā„¢ healthcare database,ā€ published in the May 2025 issue of BMC Nephrology by Uriol-Rivera et al. Atypical hemolytic uremic syndrome (aHUS) was recognized as a thrombotic microangiopathy (TMA), microangiopathic hemolytic anemia causing end organ damage and death without treatment, highlighting the importance of quickly distinguishing it from other TMA forms for optim

Clinic 52
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Gender Disparities and Treatment Gaps in LDL-C

Physician's Weekly

The following is a summary of ā€œBridging Gaps in LDL-C Management: Utilization of Lipid-Lowering Therapies, Gender Disparities, and the Impact of Cardiology Visits on Secondary Prevention,ā€ published in the June 2025 issue of American Journal Cardiology of by Sedrakyan et al. Researchers conducted a retrospective study to evaluate the real-world use of novel lipid-lowering therapies and their impact on achieving LDL-C targets.

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Reduced Colon Dysplasia Risk After Liver Transplant in PSC-IBD

Physician's Weekly

The following is a summary of ā€œLiver Transplantation Is Associated With a Reduced Risk of Colorectal Dysplasia in Patients With IBD and Concomitant PSC,ā€ published in the June 2025 issue of Clinical Gastroenterology and Hepatology by Coelho-Prabhu et al. Primary sclerosing cholangitis (PSC) affected up to 8% of individuals with inflammatory bowel diseases (IBDs) and was related to an increased risk of colorectal neoplasia (CRN), potentially related to altered bile acid composition, with approx

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Comparing Cognition in CRPS and CTS

Physician's Weekly

The following is a summary of ā€œCognitive Function in Patients With Complex Regional Pain Syndrome: No Clear Impairment Found in a Select Patient Sample,ā€ published in the June 2025 issue of European Journal of Pain by Berg et al. Chronic pain impact on cognition suggests complex regional pain syndrome (CRPS) may impair specific cognitive functions, but limited assessments have left affected domains and CRPS-specific impairments unclear.