KevinMD
JUNE 29, 2025
For as long as I can remember, I’ve wanted to be a physician. My journey to medicine is not unique. My motivations ring familiar to all health care workers. Many medical students are cut from the same cloth in this regard. We want to help people, to use science to alleviate human suffering, and to Read moreā¦ Why medical student debt is killing primary care in America originally appeared in KevinMD.com.
Physician's Weekly
JUNE 29, 2025
NIPPV emerged as the most effective preoxygenation method to reduce hypoxemia during intubation, offering valuable guidance for critical care practice. A study published in the June 2025 issue of Lancet Respiratory Medicine emphasized the critical role of preoxygenation before intubation and explored the uncertain comparative effectiveness of strategies such as facemask oxygen, high-flow nasal cannula (HFNC), and non-invasive positive pressure ventilation (NIPPV).
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KevinMD
JUNE 29, 2025
Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes! Surgeon Suhaib J. S. Ahmad discusses his article, “Why even the best employees are silently quitting health care.” Suhaib explores the phenomenon of highly competent and once-passionate health care professionals disengaging and leaving their roles, often without overt complaint.
Physician's Weekly
JUNE 29, 2025
Diffusion basis spectrum imaging combined with AI enhances diagnostic accuracy for prostate cancer A study published in the June 2025 issue of the Journal of Urology evaluated artificial intelligence models applied to diffusion basis spectrum imaging metrics for predicting clinically significant prostate cancer before biopsy. They assessed 241 patients who underwent prostate magnetic resonance imaging with conventional and diffusion basis spectrum imaging sequences before biopsy between Feb
KevinMD
JUNE 29, 2025
Many of the physicians we work with are highly disciplined, generous with their time, and deeply committed to their profession. They spend years in training, work demanding hours, and carry an enormous sense of responsibility. Yet even with strong incomes and responsible habits, many still feel uncertain about their long-term financial picture. The problem is Read moreā¦ 5 blind spots that stall physician wealth originally appeared in KevinMD.com.
Physician's Weekly
JUNE 29, 2025
Pairing music with awakening trials reduced sedation exposure and improved comfort and clarity in individuals receiving mechanical ventilation in the ICU. A study published in the June 2025 issue of J ournal of Intensive Care Medicine by researchers was conducted to determine whether protocolized music intervention paired with spontaneous awakening trials (SAT) was a feasible approach to reduce sedation exposure in individuals on mechanical ventilation and sedated intensive care unit (ICU).
Mere Mortal MD
JUNE 29, 2025
I just returned from a week long vacation in the remote mountains of Alaska, in a tiny little town called McCarthy. This magical place is located in the Wrangell St. Elias National Park & Reserve, which is the largest National Park in the United States. The Park contains sections of 4 different mountain chains: the Chugach Mountains, the Wrangell Mountains, the Saint Elias Mountains, and the Alaska Range.
Primary Care Digest brings together the best content for architecture professionals from the widest variety of industry thought leaders.
FDA Law
JUNE 29, 2025
By VĆ©ronique Li, Senior Medical Device Regulation Expert & Jeffrey N. Gibbs ā The Federal Food, Drug, and Cosmetic Act (FD&C Act) has very different regulatory regimes for pharmaceutical products than devices. Knowing how a product will be regulated is essential to companies. The means to gaining that knowledge for combination products or single entity products where the regulatory classification is unclear is the Request for Designation (RFD).
Physician's Weekly
JUNE 29, 2025
Clearer survivorship plans and better education were identified as key needs to help PCPs optimize care for cancer survivors. Researchers conducted a retrospective study published in the June 2025 issue of Journal of Cancer Survivorship to examine primary care providersā (PCPs) preferences, needs, and perceived barriers related to treatment summaries and survivorship care plans (TS/SCPs) in supporting cancer survivor care.
NPR Health
JUNE 29, 2025
Health secretary RFK Jr. has said seed oils, like canola, soybean and sunflower oil are 'poisoning Americans.' But many researchers say the evidence doesn't back up the claims.
Physician's Weekly
JUNE 29, 2025
Pembrolizumab demonstrated promising efficacy and safety in anaplastic thyroid cancer based on pooled survival and tumor response data. A study published in June 2025 issue of Clinical Endocrinology , anaplastic thyroid carcinoma (ATC) was highlighted as a rare, stage IV malignancy with a median survival of 4 months and limited response to conventional treatments.
KevinMD
JUNE 29, 2025
“I look at my baby and I don’t feel a thing,” the patient whispers as she cradles her 3-week-old baby. “I feel so much guilt … sometimes I don’t want to be here at all.” And yet, she is not alone. Her words echo the silent yet growing public health crisis of perinatal mental health. Read moreā¦ Why perinatal mental health is the top cause of maternal death in the U.S. originally appeared in KevinMD.com.
Physician's Weekly
JUNE 29, 2025
Inadequate chronic pain care under long-term opioid therapy highlights the need for better Chronic Care Model integration in outpatient settings. A study published in the June 2025 issue of BMC Primary Care on the clinical complexity of managing chronic non-cancer pain (CNCP) in outpatient settings, where long-term opioid therapy, though indicated for selected individuals, carried significant risks, necessitating structured, guideline-based care.
Physician's Weekly
JUNE 29, 2025
DNMT3A mutations emerged as potential biomarkers for enhanced immunotherapy benefit in non-small cell lung cancer. Researchers conducted a retrospective study published in June 2025 issue of Annals of Oncology to examine the association between genomic alterations and immune checkpoint inhibitor response in individuals with metastatic non-small cell lung cancer.
Physician's Weekly
JUNE 29, 2025
Expanded screening using the Vaidya & Carey algorithm significantly improved primary aldosteronism detection in patients with obstructive sleep apnea and hypertension. Researchers conducted a retrospective study published in June 2025 in the issue of Endocrine to assess whether expanding screening criteria could enhance the detection of primary aldosteronism (PA) and reduce untreated cases of secondary hypertension (HTN).
Physician's Weekly
JUNE 29, 2025
Open-source analysis of clinical interview speech revealed distinct vocal patterns linked to schizophrenia symptom severity, supporting passive digital phenotyping. A study published in the June 2025 issue of Frontiers in Psychiatry about speech as a clinically relevant marker for schizophrenia symptom severity, yet current approaches to digital phenotyping often rely on closed-source platforms that can increase the burden for both clinicians and individuals.
Physician's Weekly
JUNE 29, 2025
Targeted ablation guided by voltage mapping improved rhythm outcomes in individuals with recurrent atrial fibrillation after initial isolation. Researchers conducted a study published in June 2025 issue of Clinical Research in Cardiology to evaluate the effectiveness of repeat atrial fibrillation (AF) ablation combining pulmonary vein isolation (PVI) with substrate-based left atrial ablation targeting low voltage areas (LVA).
Physician's Weekly
JUNE 29, 2025
FLT3-ITD MRD dynamics predicted relapse risk and shaped response to gilteritinib maintenance in post-transplant AML. A study published in the May 2025 issue of Blood about MORPHO trial that evaluated gilteritinib vs placebo as maintenance therapy after hematopoietic cell transplantation (HCT) in individuals with FLT3-ITDāmutated acute myeloid leukemia (AML), focusing on pre- and post-transplant measurable residual disease (MRD).
Physician's Weekly
JUNE 29, 2025
A lifestyle program for children with cancer exhibited gains in vigorous activity. According to a study published in June 2025 in the issue of BMC Pediatrics, promoting physical activity (PA) and healthy nutrition during childhood cancer treatment is essential for supporting protective health behaviors. Researchers conducted a retrospective study to assess the changes in PA and diet quality before and after a family lifestyle intervention during cancer treatment in childhood and to examine
Physician's Weekly
JUNE 29, 2025
Women from racial minority groups experienced delayed breast cancer surgery regardless of distance traveled, revealing persistent care disparities. Researchers conducted a study published in June 2025 in the issue of American Journal of Surgery to examine whether the distance traveled to surgical facilities was associated with timely breast cancer surgery among women diagnosed with breast cancer in Georgia.
Physician's Weekly
JUNE 29, 2025
A decade-long bibliometric analysis revealed rising global interest in atopic dermatitisārelated itch, with an emerging focus on neural mechanisms and novel therapies. Researchers conducted a retrospective study published in the June 2025 issue of Frontiers in Medicine to analyze research trends and key focus areas in atopic dermatitis (AD) related itch over the past decade.
Physician's Weekly
JUNE 29, 2025
Secukinumab showed moderate effectiveness but delayed access and reduced survival in later-line use, especially among publicly insured patients. Researchers conducted a retrospective study published in May 2025 issue of Journal of Rheumatology to investigate access, effectiveness, drug survival, and adverse events (AEs) of secukinumab (SEC) in individuals with axial spondyloarthritis (axSpA) and axial psoriatic arthritis (axPsA).
Physician's Weekly
JUNE 29, 2025
Higher cardiometabolic index levels were strongly linked to all types of urinary incontinence in women. A study published in April 2025 issue of European Journal of Obstetrics and Gynecology and Reproductive Biology about Urinary incontinence (UI), closely related to metabolic conditions, and the cardiometabolic index (CMI) had emerged as a novel and easily obtainable indicator for assessing metabolic status.
Physician's Weekly
JUNE 29, 2025
Side-by-side metal stenting showed strong clinical success and low complication rates in managing unresectable malignant hilar biliary obstruction. A study published in June 2025 issue of BMC Gastroenterology underscored the clinical uncertainty surrounding simultaneous side-by-side deployment of uncovered self-expanding metal stents (SEMS) as a palliative strategy for malignant hilar biliary obstruction (MHBO).
Physician's Weekly
JUNE 29, 2025
Preoperative CT angiography helped map gluteal vessels, guiding safer screw placement in sacroiliac joint fusion. A pilot study published in June 2025 in the issue of the Journal of Pain Research reported that the lateral transiliac approach for sacroiliac (SI) joint fusion was widely used but posed a risk of injuring branches of the superior gluteal artery (SGA).
Physician's Weekly
JUNE 29, 2025
Acral lentiginous melanoma showed higher mortality in one racial group despite comparable disease severity at diagnosis. A study published in June 2025 issue of Journal of American Academy of Dermatology underscored that delayed diagnosis and greater acral lentiginous melanoma (ALM) burden contribute to poorer melanoma outcomes. Researchers conducted a retrospective study to understand the epidemiology of ALM across racial groups and determine whether outcome disparities were primarily drive
Physician's Weekly
JUNE 29, 2025
Serum uric acid levels showed an inverse, linear association with depression risk, highlighting a potential biochemical marker for mental health in U.S. Researchers conducted a retrospective study published in the June 2025 issue of Frontiers in Psychiatry to examine the association between uric acid levels and depressive symptoms among adults living with depression in the United States using data from the National Health and Nutrition Examination Survey (NHANES).
Physician's Weekly
JUNE 29, 2025
Right-heart valve deterioration traced to pacing type, revealing distinct tricuspid vulnerability with right-ventricular lead placement. Researchers conducted a retrospective study published in June 2025 issue of Clinical Research in Cardiology to compare the prevalence and progression of tricuspid regurgitation (TR) following implantation of right-ventricular (RV all ) pacing cardiac implantable electronic devices (CIEDs) implantation vs biventricular (BiV) pacing devices.
Physician's Weekly
JUNE 29, 2025
Complement activation was common but non-specific in immune-related neuropathy and myositis, questioning the utility of complement inhibitors. Researchers conducted a retrospective study published in June 2025 issue of Journal of Neurology to investigate the role of complement activation in immune-related neuropathy (irNeuropathy) and myositis (irMyositis) associated with immune checkpoint inhibitors (ICI).
Physician's Weekly
JUNE 29, 2025
Helping individuals through shared decision making led to prior dialysis planning, good treatment alignment, and improved outcomes shaped by age, frailty, and support systems. Researchers conducted a retrospective study published in the June 2025 issue of BMC Nephrology to evaluate dialysis modality selection and clinical outcomes among patients with kidney failure (KF) following a shared decision-making (SDM) intervention.
Physician's Weekly
JUNE 29, 2025
Analysis of DILIN data revealed that initial R values best predicted Hyās Law outcomes. A study published in June 2025 issue of American Journal of Gastroenterology stated that Hyās Law was associated with hepatocellular (HC) drug-induced liver injury (DILI) with jaundice to high mortality despite lacking defined timing of liver tests and clear classification criteria.
Physician's Weekly
JUNE 29, 2025
Loss of a key immune protein disrupted cell signaling and defense, revealing a novel driver of chronic airway inflammation in NSAID-sensitive disease. A study published in June 2025 issue of Journal of Allergy and Clinical Immunology stated that non-steroidal anti-inflammatory drugs (NSAID)-exacerbated respiratory disease (N-ERD) was characterized by chronic asthma, nasal polyposis (NP), and NSAID intolerance, with underlying nasal inflammatory mechanisms remaining insufficiently understood.
Physician's Weekly
JUNE 29, 2025
Antibiotic demand for pneumonia and COPD in the top 20 countries showed high global consumption. Researchers conducted a retrospective study published in the June 2025 issue of International Journal of Infectious Disease to estimate the total antibiotic requirements for treating individuals with chronic obstructive pulmonary disease (COPD). They estimated COPD exacerbations and pneumonia cases in 2019 across the 20 most populous countries.
Physician's Weekly
JUNE 29, 2025
Faster Ī±-synuclein seeding in cerebrospinal fluid signaled a higher risk of cognitive decline in Parkinsonās disease. A study published in June 2025 issue of Lancet Neurology about Ī±-synuclein seed amplification assay (SAA) as a diagnostic marker for Parkinsonās disease with limited to small, single-center studies over short follow-up periods. Researchers evaluated the diagnostic and prognostic utility of quantitative cerebrospinal fluid Ī±-synuclein SAA kinetic measures in Parkinsonās disease
Physician's Weekly
JUNE 29, 2025
Severe COVID-19 outcomes during Omicron were extremely impacted by underlying health conditions. Researchers conducted a retrospective study published in June 2025 issue of BMC Infectious Disease to compare mortality and hospitalization risks from COVID-19 during the Omicron era between individuals with comorbidities and those without. They performed a systematic search across 7 databases [Embase, MEDLINE, PubMed, Europe PMC, Latin American and Caribbean Health Sciences Literature, Cochrane
Physician's Weekly
JUNE 29, 2025
Age and female sex emerged as key drivers of acute dacryocystitis, especially in those with primary nasolacrimal duct obstruction. The study published in June 2025 in the issue of the British Journal of Ophthalmology reported that acute dacryocystitis (AD), commonly linked to nasolacrimal duct obstruction which involves surgery , posed significant health risks, especially among older adults (OAs).
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