Fri.Jan 17, 2025

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Well-being Investment: Restorative Sleep - Foundation of Self-Care

Joy in Family Medicine Coaching

(NEW) TLDR at the bottom* Welcome back to our series on physical well-being investments. Today, we’re diving into perhaps the most critical supporter of self-care, the very foundation - restorative sleep. How challenging that can be in this line of work! If you’re already waking up refreshed and energized throughout the day—keep doing what works for you.

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A chain reaction: HIV vaccines can lead to antibodies against antibodies

Medical Xpress

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection.

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Hazmat crews tackle toxic waste left behind by LA's fires

NPR Health

The fires have turned some electric car batteries and household items into "unexploded ordnances," says an EPA official tasked with the cleanup (Image credit: David Crane/MediaNews Group)

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Specific neurons with an immune 'doorbell' may influence mood and memory

Medical Xpress

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states. In disease, high levels of IL-1 in the brain are linked to neuroinflammation, which can disrupt the body's stress response, cause sickness-like behaviors, worsen inflammation by activating brain immune cells, and allow immune cells from the body to enter the brain.

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Biden's Medicaid director shares lessons learned and concerns for the program's future

NPR Health

Dan Tsai discusses how he ran Medicaid under Biden, and his fears for how Republicans might try to change the program.

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New article warns against restricting discussions on structural racism

Medical Xpress

A new Health Affairs article highlights the detrimental impact of recent state and federal policies that restrict discussions of "divisive concepts," including structural racism. It warns that these policies undermine efforts to address health inequities and improve population health.

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Zyn nicotine pouches can be marketed in the U.S., the FDA says. What does this mean?

NPR Health

The FDA said "an extensive scientific review" found the products were found to pose lower risks of cancer and other serious health conditions compared to cigarettes and smokeless tobacco products.

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Medicare targets 15 more drugs for price negotiations -- including Ozempic

NPR Health

On its last weekday in power, the Biden Administration has chosen the next batch of drugs up for price negotiation in Medicare.

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The power of cinema: Study shows film intervention reduces violence against children

Medical Xpress

A new study shows that screenings of a locally-produced narrative film about parenting led to a significant reduction in physical violence against children.

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4 key global health decisions expected from Trump

NPR Health

Four key decisions await Trump: reinstating the Mexico City Policy; withdrawing from WHO, abandoning the Pandemic Prevention Treaty and de-authorizing PEPFAR, the HIV prevention program.

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AI can guide acquisition of diagnostic-quality lung ultrasound images

Medical Xpress

Trained health care professionals (THCPs), including medical assistants, respiratory therapists, and nurses, with artificial intelligence (AI) assistance can achieve lung ultrasound (LUS) images with diagnostic quality that does not differ significantly from that achieved by experts, according to a study published online Jan. 15 in JAMA Cardiology.

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How will Trump's return to the White House change the face of global health?

NPR Health

When Donald Trump returns to the White House, he's expected to issue a series of orders with far-reaching impact on global health from abortion services to support for the World Health Organization.

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Interdisciplinary research lays groundwork for predicting if bone cancer will spread

Medical Xpress

Bone pain. Joint pain. Bone swelling. These are symptoms that about 1,000 people in the United States begin to feel each year shortly before being diagnosed with osteosarcoma, a type of cancer that starts in the bones. Although any age can develop osteosarcoma, approximately half of diagnosed cases are in children and adolescents.

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Megakaryocytes' immune characteristics and role elucidated

Medical Xpress

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts. Recent advances in technology have unveiled the diverse immune functions of MKs, which express immune sensors and participate in immune activities, thus expanding their traditional role beyond hemostasis and coagulation.

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New animal model offers insights into pancreatic disease and diabetes

Medical Xpress

Cystic fibrosis (CF) is a life-threatening genetic disease affecting multiple organ systems, with pancreatic dysfunction representing a critical and often overlooked complication. A recent study published in eGastroenterology introduces young rabbits with CF as a novel and accessible model to study CF-related pancreatic endocrine pathology. This model offers an unprecedented opportunity to deepen our understanding of CF-related diabetes (CFRD), a condition affecting up to 50% of adults with CF.

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Pandemic led to rapid adoption of telemental health for those with schizophrenia

Medical Xpress

For Medicaid beneficiaries with schizophrenia, delivery of mental health care through telehealth (telemental health care) diffused rapidly after onset of the COVID-19 pandemic, according to a study published online Jan. 16 in JAMA Network Open.

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Early pregnancy weight gain tied to fetal fat buildup

Medical Xpress

Fetuses of pregnant people who gained excess weight in the first trimester of pregnancy show signs of excess fat distribution in the upper arm and in the abdomen, according to a study by researchers at the National Institutes of Health. These findings may inform efforts to prevent excessive weight gain early in life, a risk factor for adult obesity and related conditions, such as heart disease, high blood pressure and diabetes.

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FDA approves marketing of nicotine pouches

Medical Xpress

Following an extensive scientific review, the U.S. Food and Drug Administration has authorized the marketing of 20 ZYN nicotine pouch products. Nicotine pouchessmall synthetic fiber pouches containing nicotineare designed to be placed between a person's gum and lip.

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Neuroimaging reveals 94% of gray matter in brains of mothers undergoes changes during pregnancy

Medical Xpress

A study led by the UAB has analyzed the brains of women during pregnancy for the first time using neuroimaging techniques. The study included non-pregnant mothers, whose partners were pregnant, to distinguish biological effects from those caused by the experience of being a mother. The research shows that there is a reduction and partial recovery of almost 5% of gray matter in 94% of the total gray matter volume of the brain, especially in regions linked to social cognition.

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Brain-controlled interface experiment provides empirical support for one-way neural activity paths

Medical Xpress

Neural network models that are able to make decisions or store memories have long captured scientists' imaginations. In these models, a hallmark of the computation being performed by the network is the presence of stereotyped sequences of activity, akin to one-way paths. This idea was pioneered by John Hopfield, who was notably co-awarded the 2024 Nobel Prize in Physics.

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Fluorescent probes illuminate cholesterol and Alzheimer's research

Medical Xpress

The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of chemistry and biochemistry at Florida Atlantic University's Charles E. Schmidt College of Science, believes the key may lie in understanding how cholesterol and other lipids move through cells and affect their communication.

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Researchers propose novel model to screen misreporting in dietary surveys

Medical Xpress

An international team led by Prof. John Speakman from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences derived a predictive model by combining classical statistics and machine learning for total energy expenditure, providing a more objective way to assess the validity of food intake records.

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New criteria developed for appropriate use of cognitive impairment imaging tools

Medical Xpress

Appropriate use criteria (AUC) for the use of amyloid and tau positron emission tomography (PET) have been issued by the Alzheimer's Association and the Society for Nuclear Medicine and Molecular Imaging and published online Jan. 8 in both Alzheimer's & Dementia and the Journal of Nuclear Medicine.

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Key enzyme identified as potential target for cancer immunotherapy

Medical Xpress

Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzymeP4HA1 prolyl hydroxylase, is strongly induced in CD8+ T cells in solid cancer, the primary immune cells involved in combating cancer. P4HA1 causes disruptions in energy production within the cells, which leads to weaker immune cells that are less able to fight cancer and form long-lasting anti-cancer immunity, highlighting P4HA1 as a promising target for treating solid tumors.

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Hairstylists serving Black and Latina clients exposed to high concentrations of airborne toxins

Medical Xpress

Hairstylists, especially those providing services to Black and Latina women, are exposed to high concentrations of harmful airborne chemicals in their workplace, a team of Johns Hopkins researchers has found.

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New diagnostic criteria for LATE dementia offer hope for improved care

Medical Xpress

Researchers at the University of Kentucky's Sanders-Brown Center on Aging are at the forefront of advancing dementia research with groundbreaking work on a condition known as LATE, or "limbic predominant age-related TDP-43 encephalopathy.

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Phase 2 results suggest continued study of novel first-line combo for advanced kidney cancer

Medical Xpress

In the open-label phase 2 LITESPARK-003 study, led by Dana-Farber Cancer Institute's Toni Choueiri, MD, researchers investigated for the first time the combination of cabozantinib, an anti-angiogenic agent, plus belzutifan, a first-in-class HIF-2 inhibitor. The findings are published in The Lancet Oncology journal.

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Q&A: Transplant treatment for diabetes shows promising results

Medical Xpress

A completely new way of treating type 1 diabetes is being tested at Uppsala University Hospital. Patients are being offered transplants of genetically modified insulin-producing cells and the initial results are promising. We put a few questions to Per-Ola Carlsson, Professor of Medical Cell Biology, who is leading the study.

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Unraveling the impact of solid tumor dissociation methods

Medical Xpress

Cancer remains one of the most complex diseases, with its diverse molecular profiles and cellular compositions posing significant challenges for treatment. Traditional methods of cancer research, such as two-dimensional cell cultures and animal models, often fail to capture the full complexity of human cancers, particularly the three-dimensional structures and microenvironmental interactions of solid tumors.

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Drop in episiotomy not tied to increase in obstetric anal sphincter injury for most women

Medical Xpress

A significant overall reduction in the prevalence of episiotomy in France from 2010 to 2021 has not been followed by an overall increase in obstetric anal sphincter injury (OASI), according to a study published online Jan. 14 in PLOS Medicine.

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Exploring exercise-induced arterial adaptations in college baseball players

Medical Xpress

Researchers at University of Tsukuba conducted a detailed investigation on exercise-induced arterial adaptations (changes in arterial structure and function associated with sport-specific demands) among college baseball players.

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Sepsis molecule discovery could lead to improved treatments for critically ill patients

Medical Xpress

Researchers at Oregon Health & Science University have uncovered how a molecule found on certain bacteria may drive blood clotting in sepsis, a life-threatening condition that causes about 8 million deaths per year.

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Higher costs can limit attendance for life changing cardiac rehab

Medical Xpress

Despite the success cardiac rehabilitation has shown at reducing heart-related deaths and hospital readmissions, higher out-of-pocket costs may prevent patients from participating in the program, a Michigan Medicine study suggests.

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2011 to 2022 saw increasing prevalence of poor mental health

Medical Xpress

Poor mental health was increasingly prevalent from 2011 to 2022, with inequities discernible by age, sex, and racial and ethnic group, according to a research letter published online Jan. 15 in JAMA Network Open.