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Oral versus intravenous antibiotics for the initial treatment of acute pyelonephritis in adults: a systematic review [Acute and emergency care]

Annals of Family Medicine

Context Acute pyelonephritis is a common diagnosis in the primary care and emergency settings. These include minimizing resource utilization and decreasing the risk of complications associated with IV antibiotics such as diarrhea. Setting Studies conducted in the ED, in urgent care centers or in outpatient clinics were included.

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Advancing Biomarker Validation for Drug Hypersensitivity

Physician's Weekly

But the varied mechanisms and clinical presentations of drug hypersensitivity reactions (DHRs) can make diagnosis and treatment challenging, and most biomarkers still require validation. The biomarkers of clinical utility are skin tests , specific IgE (sIgE), tryptase , and some HLA-DR genotyping.

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Clinical Reasoning Corner: Pre and Posttest Probability – Jack Penner

The Clinical Problem Solvers

Objectives Define pre and posttest probability Demonstrate the utility of pre and posttest probability in diagnostic reasoning Practice applying pre and posttest probability in clinical decision making What are Pre and Posttest Probabilities? moving them much lower on our differential): pre and posttest probabilities. Let’s dive in!

Clinic 52
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Postural Sway Velocity Effective for Assessing Diabetic Peripheral Neuropathy

Physician's Weekly

Several sessions included presentations on diabetic peripheral neuropathy (DPN), such as the Peter J. In one study that was not presented at the PNS annual meeting, the researchers aimed to assess whether evaluating balance and gait could serve as a viable screening tool of DPN. Dyck Lecture on mechanisms of diabetic neuropathic pain.

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Clinical Reasoning Corner: Illness Script

The Clinical Problem Solvers

Demonstrate the utility of an illness script in clinical reasoning 4.- In the reasoning process, we use illness scripts to compare and contrast a patient’s clinical presentation (i.e., our own illness scripts) as we reason to a working diagnosis or a final diagnosis. Today we are going to talk about Illness scripts !

Illness 52
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Better Care Models Needed for Young Adults With Obesity

Physician's Weekly

Obesity drugs were not utilized often in young adults and adolescents despite high complication rates, prompting researchers to call for chronic, holistic care. The retrospective analysis incorporated data from Optum MarketClarity claims and electronic medical records. The data spanned from January 2019 to March 2024.

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Ambulatory Behavioral Health Referral Patterns in the Setting of Chronic Medical Conditions [Behavioral, psychosocial, and mental illness]

Annals of Family Medicine

Early identification and intervention in behavioral aspects of chronic diseases leads to improved function with decreased healthcare utilization, yet we know little about referral patterns for behavioral support of chronic disease. Our work builds a foundation for cost-effective workflows to support patients with multimorbidity.

Referral 130