Diagnose Diagnosis Presentation Utilities 
Physician's Weekly
JUNE 16, 2025
Biomarkers for drug-induced immune reactions aid clinicians in diagnosing, risk-stratifying, and managing diseases. But the varied mechanisms and clinical presentations of drug hypersensitivity reactions (DHRs) can make diagnosis and treatment challenging, and most biomarkers still require validation.
The Clinical Problem Solvers
OCTOBER 23, 2019
For our first post, we are going to talk about two concepts that help us decide whether we treat, test for, or toss specific diagnoses (i.e., Let’s practice with a case: You are called to admit a 72 year-old woman with hypertension, diabetes, and knee replacement seven days prior who presents with acute, pleuritic chest pain and dyspnea.
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Physician's Weekly
JUNE 17, 2025
Several sessions included presentations on diabetic peripheral neuropathy (DPN), such as the Peter J. In one study that was not presented at the PNS annual meeting, the researchers aimed to assess whether evaluating balance and gait could serve as a viable screening tool of DPN. Dyck Lecture on mechanisms of diabetic neuropathic pain.
PEMBlog
SEPTEMBER 20, 2023
Constipation is a clinical diagnosis and does not require testing, yet as many as 70% of children who are given a diagnosis of constipation in the emergency department have an abdominal x-ray completed. The diagnosis of constipation should be made based on a good history and clinical exam.
Physician's Weekly
JUNE 17, 2025
It presents in different ways. It presents across multiple domains of disease. So for example, peripheral arthritis, enthesitis dactylitis, skin involvement, axial disease, no one PSA patient presents the same exact way. So I think it leads to a lot of uncertainty in terms of, am I going to get a diagnosis?
The Clinical Problem Solvers
FEBRUARY 9, 2020
Objectives Define likelihood ratios and their utility in diagnostic reasoning Identify how likelihood ratios alter the probability of a diagnosis Apply likelihood ratios in clinical reasoning What are likelihood ratios and how do they work? A LR > 1 increases the probability of a specific diagnosis.
PEMBlog
OCTOBER 26, 2023
The most common presentation in children under 5 years of age is rectal bleeding, which may be intermittent or massive. This nuclear medicine scan utilizes a radioactive tracer that is taken up by the gastric mucosa in Meckel’s diverticulum, thereby helping to identify its presence. .” The bleeding is usually painless.
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