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SGLT-2 inhibitor, cardiovascular risk and outcome in patients with comorbidity of hypertension and diabetes [Cardiovascular disease]

Annals of Family Medicine

Context Two thirds of diabetes patients complicated with hypertension, and comorbidity increase 4-fold risk of atherosclerotic cardiovascular disease (ASCVD). Population Studied individuals with comorbidity of hypertension and type 2 diabetes. Setting or Dataset Five electronic systems of community clinic.

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How to manage GLP-1s in the hospital

Today's Hospitalist

THE BLOCKBUSTER GLP-1 receptor agonists are a transformative class of medications increasingly tied to better outcomes across a variety of conditions and organ systems, not just in patients with obesity and type 2 diabetes. That’s according to two internists who work closely with hospitalized patients who take GLP-1s.

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Guidelines or Goals in Heart Failure: A Podcast with Parag Goyal, Nicole Superville, and Matthew Shuster

GeriPal

We talk about what is heart failure, particularly HFpEF, how we treat it (including the use of sodium–glucose cotransporter-2 inhibitors (SGLT2’s), and how we should apply guidelines to individual patients, especially those with multimorbidity who are taking a lot of other medications. But we’re not perfect individuals.

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On Racism & Ageism: Ramona Rhodes, Sharon Brangman, Tim Farrell, and Nancy Lundebjerg

GeriPal

Second, as we discussed in last week’s podcast , older adults, particularly those in nursing homes, were far more likely to die than younger individuals. We lump everybody who’s 65 and older together, and then we don’t look at the individual characteristics of that person, so we fall into these patterns based on racial premises.

IT 91
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Redefining Alzheimer’s Disease: A Podcast with Heather Whitson, Jason Karlawish, Lon Schneider

GeriPal

You can easily have fibrinoid necrosis of your kidneys and not have hypertension, but the pathology of hypertension is most commonly associated with fibrinoid necrosis. Jason: You could have hypertension and have no signs and symptoms. So too systolic hypertension in elderly people, clinical trials. You can see it.

IT 115