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Portable Assay Offers Rapid, Low-Cost TB Diagnoses

Physician's Weekly

Researchers have engineered a portable “lab‑in‑tube” (LIT) assay that detects Mycobacterium tuberculosis (Mtb) DNA directly from blood, saliva, or sputum in less than 60 minutes at a relatively low cost, according to a study published in Science Translational Medicine.

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Reducing The Effort for Performing Systematic Reviews Using Natural Language Processing And Large Language Models [Systematic review, meta-analysis, or scoping review]

Annals of Family Medicine

Objective The aim is to evaluate the feasibility of an instructed large language model (LLM) to assist with human synthesis such as temporal topic search and screening by citation in systematic reviews for Brain-Heart-Interconnectome (BHI) to support reporting guidelines, such as CONSORT and SPIRIT.

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The Future Of Vision And Eye Care

The Medical Futurist

The 80-year-old Ray Flynn lost his central vision entirely, but with the help of the retinal implant, he could make out shapes on the computer screen. Running trials in animals will take additional engineering and safety tests. Experts even say the eye is an ideal place to start for the first clinical use of CRISPR.

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How Your Emotional Health Impacts Blood Pressure

Imperial Center Family Medicine

It’s similar to revving a car engine for too long while staying still. People with clinical depression often have elevated cortisol levels, potentially leading to high blood pressure over time. However, chronic stress keeps your body in a continuous state of high alert.

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Hearing Loss in Geriatrics and Palliative Care: A Podcast with Nick Reed and Meg Wallhagen

GeriPal

Was there any mention about the impact that hearing loss has in communication or what we should do about it in clinical practice? Screening for addressing hearing loss should be an integral part of what we do in geriatrics and palliative care, but it often is either a passing thought or completely ignored. I’m guessing not.

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FDA’s New Draft Guidance on 510(k) Implant Devices: What You Need to Know

FDA Law Blog

airport security screening), or surgical procedures, as well as the potential for reoperation or revision of the implant. Non-Clinical Recommendations The draft guidance highlights non-clinical review areas that are generally relevant across 510(k) Implants and offers recommendations for performance data to include in a 510(k) submission.

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Mastering Responses to FDA 510(k) AI Letters: A Strategic Approach

FDA Law Blog

When a firm submits a Traditional 510(k), FDA first performs the acceptance review to determine whether a submission is administratively complete, or passes the technical screening for an electronic submission submitted using the eSTAR. An AI letter typically begins with the most significant deficiencies.