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Oral versus intravenous antibiotics for the initial treatment of acute pyelonephritis in adults: a systematic review [Acute and emergency care]

Annals of Family Medicine

Context Acute pyelonephritis is a common diagnosis in the primary care and emergency settings. These include minimizing resource utilization and decreasing the risk of complications associated with IV antibiotics such as diarrhea. Setting Studies conducted in the ED, in urgent care centers or in outpatient clinics were included.

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Clinical Reasoning Corner: Likelihood Ratios

The Clinical Problem Solvers

Clinical Reasoning Corner: Likelihood Ratios By Jack Penner Welcome back, Clinical Problem Solvers! Thank you for reading the latest post in our “Clinical Reasoning Corner”, where we discuss key clinical reasoning principles that shape how we think through cases. To do that, we need to rely on LRs. Luckily, Dr.

Clinic 52
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WDx Clinical Unknown with Dr. Steph Sherman and the CPSolvers

The Clinical Problem Solvers

[link] Dr. Steph Sherman, Lindsey , Emma , and Sharmin tackle a case presented by Anna Want to learn more about Women in Diagnosis (WDx) series? She spends her free time with her husband, fellow clinical problem solver Zaven Sargsyan, and their ever-more-mobile 8-month-old son. Blog post – by Smitha Want to test your learning?

Clinic 52
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Dementia complicates cancer care, increasing risk of poorer clinical outcome and patient experience

Medical Xpress

Pre-existing dementia complicates cancer care and increases the risk of worse clinical outcomes and inferior patient experience, according to a review of studies exploring the intersection of dementia and cancer.

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A deeper dive into GPA – Jack Penner

The Clinical Problem Solvers

Welcome back, Clinical Problem Solvers! A lung biopsy demonstrated necrotizing granulomatous inflammation, and a diagnosis of GPA was made. Clinical Manifestations We often think of GPA as a pulmonary-renal syndrome, but, while many patients develop renal complications, a much smaller percentage present with them.

Illness 52
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Why Identifying and Managing Giant Cell Arteritis as an Emergency Is Crucial

Physician's Weekly

Leonard Calabrese, DO, Paras Karmacharya, MD, MS, and Adam Kilian, MD, break down why giant cell arteritis (GCA) demands immediate action, explain how to confirm diagnosis quickly, and what same-day treatment options like upadacitinib (Rinvoq) mean for patient care. But treatment first, securing the diagnosis is secondary and often delayed.

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Lupus Emergencies in Children and Adolescents

PEMBlog

In pediatric patients, complications can evolve rapidly and carry significant morbidity and mortality. ED referrals are often prompted by incidental findings of proteinuria or hematuria, or clinical concerns for hypertensive encephalopathy or PRES. Avoid transfusion unless clinically necessary.