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Clinical Reasoning Corner: Pre and Posttest Probability – Jack Penner

The Clinical Problem Solvers

Let’s practice with a case: You are called to admit a 72 year-old woman with hypertension, diabetes, and knee replacement seven days prior who presents with acute, pleuritic chest pain and dyspnea. we’re more likely to test for a “can’t miss” diagnosis even if our pretest probability is very low), the morbidity of the treatment (e.g.

Clinic 52
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Clinical Reasoning Corner: Likelihood Ratios

The Clinical Problem Solvers

Objectives Define likelihood ratios and their utility in diagnostic reasoning Identify how likelihood ratios alter the probability of a diagnosis Apply likelihood ratios in clinical reasoning What are likelihood ratios and how do they work? A LR > 1 increases the probability of a specific diagnosis. Is the ascitic fluid infected?

Clinic 52
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Reasoning during the COVID-19 pandemic

The Clinical Problem Solvers

No prior history of atrial fibrillation – just hypertension and diabetes. Would I’ve been able to reason my way to his underlying diagnosis from the initial data? I find it awe-inspiring to listen to clinicians pick up on subtle clues and use both intuitive and analytic reasoning to reach a final diagnosis.

Illness 52
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Subclavian Steal Syndrome

Vascular Physician

Type I – Antegrade vertebral flow is reduced Type II – Antegrade flow during diastolic phase and retrograde flow during systolic phase Type III – Permanent retrograde vertebral flow Diagnosis Diagnosis can be made using imaging such as duplex ultrasound of the subclavian and vertebral arteries.

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Problem Representation

The Clinical Problem Solvers

A problem representation (PR, or Summary Statement) is an evolving, concise summary that highlights the defining features of a case , helping clinicians generate a focused differential diagnosis and identify the next steps in diagnosis and treatment. His past medical history is significant for hypertension and diabetes mellitus.

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Lipodermatosclerosis

Vascular Physician

Etiology: a chronic form of stasis dermatitis resulting from venous hypertension that causes increased capillary permeability and allows leakage of fibrinogen and erythrocytes into the dermis. Diagnosis: clinical, often seen with other symptoms of venous insufficiency including venous varicosities, pitting edema and hyperpigmentation.

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Arterial vs. Venous Ulcers of the Lower Extremity

Vascular Physician

Hypertension and smoking are two major risk factors that may damage the most inner part of the arteries called the intima, leading to local inflammation and fibrosis that increase the resistance of the vessels and therefore restrict blood flow. Symptoms may be exacerbated by obesity, inactivity, metabolic diseases, pregnancy, and aging.