The Clinical Problem Solvers

JUNE 12, 2022

Clinical Reasoning Corner: Problem Representation By: Marcela A. de Oliveira Santana and Franco Murillo Reviewed by: Jack Penner Welcome back, Clinical Problem Solvers! The problem representation during the clinical reasoning process The PR is linked to hypothesis-generation and can act as a guide during the diagnostic journey.

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PEMBlog

SEPTEMBER 20, 2023

This is a blog post designed to disseminate the important work of Choosing Wisely , an initiative of the the American Board of Internal Medicine Foundation, the goal of which is the spark conversations between clinicians and patients about what tests, treatments, and procedures are needed – and which ones are not.

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Common Sense Family Doctor

MAY 1, 2025

The POUND mnemonic (ie, pulsatile quality, one-day duration, unilateral headache, nausea or vomiting, disabling intensity) can help clinicians make the diagnosis of migraine in primary care, and the Migraine Disability Assessment (MIDAS) quantifies headache severity.

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Primary Care Family Physician Clinical Practice Diagnose 52

The Clinical Problem Solvers

MAY 14, 2020

Would I’ve been able to reason my way to his underlying diagnosis from the initial data? I find it awe-inspiring to listen to clinicians pick up on subtle clues and use both intuitive and analytic reasoning to reach a final diagnosis. Parenthetically, the question around CT for the diagnosis of COVID-19 is interesting.

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The Clinical Problem Solvers

AUGUST 25, 2019

Welcome back, Clinical Problem Solvers! A lung biopsy demonstrated necrotizing granulomatous inflammation, and a diagnosis of GPA was made. Clinical Manifestations We often think of GPA as a pulmonary-renal syndrome, but, while many patients develop renal complications, a much smaller percentage present with them.

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The Clinical Problem Solvers

OCTOBER 28, 2020

Her clinical interest is in endocrine surgery, with a focus in thyroid cancer. She is an NIH-funded investigator and author of more than 325 peer-reviewed publications and 78 book chapters and reviews, all largely focused on outcomes research, health care delivery, hyperparathyroidism, and thyroid cancer, with a focus on clinical trials.

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Specialization Diagnosis Education Clinic 52

The Clinical Problem Solvers

JULY 29, 2020

Want to learn more about Women in Diagnosis (WDx) series? Blog post – by Smitha [link] Episode Description Emma , Lindsey and Sharmin tackle a case presented by Sarah.

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Clinic Diagnosis 52

Common Sense Family Doctor

DECEMBER 14, 2024

Concerns about overdiagnosis of clinically insignificant prostate cancer through prostate specific antigen (PSA) screening motivated the 2018 American Academy of Family Physicians’ (AAFP) recommendation against routine screening for prostate cancer. Watchful waiting refers to clinical observation only. A recent analysis of the U.S.

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Routine Screenings Screening Complication Diagnose 52

FDA Law Blog

OCTOBER 16, 2023

discusses several approaches that companies are exploring for use of AI in the diagnosis of Alzheimer’s Disease, including AI-enabled software for retinal scans and identification of genetic triggers. The first article—“Is the Eye the Window to Alzheimer’s?”—discusses

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The Clinical Problem Solvers

SEPTEMBER 28, 2019

If you’re anything like me, you’ve probably found yourself asking that question after listening to a discussant on the podcast arrive at some unexpected diagnosis, only to have the biopsy or lab test prove them right. These clinicians recount rigorous efforts directed towards improving their knowledge and clinical skills.

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Lab Testing Clinic Education Clinical Practice 52

PEMBlog

JUNE 26, 2025

In this episode of PEM Currents: The Pediatric Emergency Medicine Podcast, we explore the clinical pearls behind “no-zone” management, how to distinguish hard and soft signs, when to image versus operate, and why airway always comes first. Penetrating neck injuries in children are rare—but when they happen, the stakes are high.

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Management Transportation Patient-Centered IT 59

FDA Law Blog

OCTOBER 14, 2024

The District Court in this case, which came to the opposite conclusion and is now reversed, was a notable outlier in a string of cases in other circuits upholding FDA’s authority to regulate stem cell clinics on similar grounds as the Ninth Circuit did here. Stem Cell Clinic, LLC , 998 F.3d Regenerative Sciences, LLC , 741 F.3d

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FDA Law Blog

DECEMBER 12, 2022

This blog post describes the medical device determination process and a way of assessing software functions to determine if your software product is subject to FDA regulations. or other similar or related article” which is “intended for use in the diagnosis of disease or other conditions.” Clinical Decision Support Software.

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Priority Physicians

JANUARY 20, 2025

In our direct primary care setting, we take the time to deep-dive and explain options to our patients so they’re comfortable with a diagnosis and treatment plan that might not require an X-ray. An MRI augments and adds confidence to our clinical diagnosis. Imaging isn’t always required to get them there.

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Management Primary Care Physician Primary Care Patient-Centered 52

Vascular Physician

FEBRUARY 13, 2022

Patients may find that medications including antihistamines (especially 1st generation), dopamine receptor antagonists, and select antidepressants worsen or even cause their RLS symptoms Diagnosing RLS Restless Leg Syndrome is a clinical diagnosis requiring all five of the following clinical features.

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Clinic Medical Diagnose Diagnosis 52

Vascular Physician

MARCH 25, 2022

Type I – Antegrade vertebral flow is reduced Type II – Antegrade flow during diastolic phase and retrograde flow during systolic phase Type III – Permanent retrograde vertebral flow Diagnosis Diagnosis can be made using imaging such as duplex ultrasound of the subclavian and vertebral arteries.

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Hypertension Treatment Plan Diabetes Diagnosis 52

Vascular Physician

APRIL 25, 2022

Diagnosis: clinical, often seen with other symptoms of venous insufficiency including venous varicosities, pitting edema and hyperpigmentation. . - Chronic phase: hyperpigmented red-brown or violet-brown discoloration and indurated skin that constricts the ankle region, resulting in an "inverted champagne bottle" appearance.

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Hypertension Diagnosis Management Clinic 52

FDA Law Blog

JUNE 3, 2025

Houck We appreciate receiving feedback on our blog posts. The assertion that prescribing immediate-release opioids longer than two or three months is a red flag may have originated with the Center for Disease Control and Prevention (CDC) 2022 Clinical Practice Guideline for Prescribing Opioids for Pain. By Larry K. Recommendation 1.

Clinical Practice 59

Clinical Practice Patient-Centered Patients Clinic 59

FDA Law Blog

OCTOBER 30, 2022

FDA is also proposing updates to Section III of the 2018 Breakthrough Devices Program guidance to clarify the designation considerations for the first breakthrough criterion—whether a device provides for “more effective” treatment or diagnosis.

Diagnosis 59

Diagnosis Clinic Provider IT 59

FDA Law Blog

AUGUST 23, 2022

The 80% sensitivity requirement for antigen tests has yet to be explained either scientifically or clinically by the Agency. While this was a step in the right direction, only the tests whose clinical studies occurred during the Omicron surge had this stipulation included in their labeling.

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PEMBlog

SEPTEMBER 27, 2023

This is a blog post designed to disseminate the important work of Choosing Wisely , an initiative of the the American Board of Internal Medicine Foundation, the goal of which is the spark conversations between clinicians and patients about what tests, treatments, and procedures are needed – and which ones are not. isolation for SARS-CoV-2).

Patients 52

Patients Illness Hospital Management 52

FDA Law Blog

SEPTEMBER 26, 2024

What no one should find funny is how CDRH seems to be approaching Breakthrough devices of late, setting clinical study expectations so high that these innovative, novel, life-saving products may never get to the other side of the door, regardless of how much they knock. CDRH takes great pride in stating that it is committed to innovation.

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PEMBlog

AUGUST 30, 2023

This is a blog post and a podcast episode designed to disseminate the important work of Choosing Wisely , an initiative of the the American Board of Internal Medicine Foundation, the goal of which is the spark conversations between clinicians and patients about what tests, treatments, and procedures are needed – and which ones are not.

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Asthma Electronics Utilities Clinical Practice 52

The Clinical Problem Solvers

DECEMBER 3, 2019

Case: Mrs. G is a 66-year-old woman with a past medical history of insulin-dependent diabetes and peripheral artery disease admitted from clinic with concern for left ankle and foot cellulitis. Why isn’t she getting better? Dx Issues: The first step in investigating potential “antibiotic failure” is to reevaluate our working diagnosis.

Diagnosis 52

Diagnosis Diabetes Diagnose Clinic 52

FDA Law Blog

OCTOBER 6, 2023

There is much to unpack, and we intend to do so in a series of blog posts. The brevity of this change belies the foreseeably seismic impact of FDA regulation of clinical laboratories on the healthcare system. In this post, we focus on the proposed changes themselves, and the many questions the agency leaves unanswered.

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FDA Law Blog

MARCH 16, 2023

The test is intended for use as an aid in the diagnosis of SARS-CoV-2 infections (COVID-19) in symptomatic individuals when tested at least twice over three days with at least 48 hours between tests. In the best tradition of teasers, keep reading our blog. symptomatic) when testing is started within 6 days of symptom onset.

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Healthcare Professional Specialization Diagnosis Transportation 40

PEMBlog

OCTOBER 2, 2024

I’ll dive into the latest clinical practice guidelines and discuss evidence-based approaches to diagnosis and treatment. Understanding dyspepsia and its clinical presentation. Now, in the pediatric emergency department, the diagnosis of reflux is primarily clinical. Alright, let’s scope things out.

Diagnosis 52

Diagnosis Management IT Patient-Centered 52

FDA Law Blog

APRIL 20, 2021

Certain types of clinical decision-support software. Calculator/Data Processing Module for Clinical Use. Remove non-device software functions intended for transferring, storing, converting formats, or displaying clinical laboratory test or other device data and results. 21 C.F.R.). Device Type. Modification. 892.2010.

Electronics 40

Electronics Medical Management Clinic 40

GeriPal

MARCH 14, 2024

Eric: Well, before we talk about dysphagia and revisit it, which is also interesting, because this is our first podcast, I think on dysphagia, but we’ve talked about it before on GeriPal, in our blog. I think someone has a song request for Alex. Raele: I do. I have one. Change by Blind Melon. Eric: Why did you choose this? Eric: Fancy.

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IT Patient-Centered Hospital Individual 125

FDA Law Blog

JUNE 22, 2023

He also identified “Next-Generation Home-based Testing Technologies, including new IVDs, Digital Lateral Flow Readers, and Reporting Technologies” as an opportunity to “extend care from the hospital and clinic into the home setting.” HbA1c, diagnosis of a particular virus, etc.). HbA1c, diagnosis of a particular virus, etc.).

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Manufacturing Clinic IT Medical 59

PEMBlog

MAY 20, 2025

(Blooms: Apply; Kirkpatrick Level 2 Learning) Evaluate the risks and benefits of ultrasound, CT, and MRI for common pediatric emergencies and identify appropriate imaging modalities based on clinical guidelines discussed in the podcast. Subspecialists are key, right? And that’s really not the case at all. and it can be overwhelming.

Families 101

Families Family Hospital Patient-Centered 101

PEMBlog

SEPTEMBER 6, 2023

This is a blog post designed to disseminate the important work of Choosing Wisely , an initiative of the the American Board of Internal Medicine Foundation, the goal of which is the spark conversations between clinicians and patients about what tests, treatments, and procedures are needed – and which ones are not. Health Aff (Millwood).

Lab Testing 52

Lab Testing Medical Patients Mental Health 52

FDA Law Blog

JANUARY 6, 2022

220 and was described on HP&M’s blog here. In general, EKRA prohibits, knowingly and willfully, soliciting, receiving, paying or offering kickbacks in exchange for referring to, inducing a referral to, or using the services of a recovery home, clinical treatment facility, or laboratory. EKRA is codified at 18 U.S.C. § 18 U.S.C. §

Lab Testing 52

Lab Testing Referral Individual Patient-Centered 52

Pamela Wible MD

JUNE 20, 2025

During that time, psychologist Herbert Freudenberger volunteered at a New York City free clinic treating addiction. He overheard the term and used it to describe himself and clinic staff in a 1974 article on staff burnout detailing long-term physical and psychological job stress. Yet moral injury is not an official diagnosis.

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FDA Law Blog

JANUARY 6, 2022

220 and was described on HP&M’s blog here. In general, EKRA prohibits, knowingly and willfully, soliciting, receiving, paying or offering kickbacks in exchange for referring to, inducing a referral to, or using the services of a recovery home, clinical treatment facility, or laboratory. EKRA is codified at 18 U.S.C. § 18 U.S.C. §

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Lab Testing Individual Referral Patient-Centered 40

FDA Law Blog

JUNE 28, 2023

The proposed definition also specifically excludes substances approved as a drug under FDC Act § 512, conditionally approved under FDC Act § 571, indexed under FDC Act § 572, or for which “substantial clinical investigations have been instituted and for which the existence of such investigations has been made public.”

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Provider Diagnose Diagnosis Clinic 45

FDA Law Blog

FEBRUARY 27, 2023

Comments, including data from research and clinical practice, that provides evidence that an alternate maximum day supply (other than the proposed 30-day supply). Proposed practitioner recordkeeping obligations. Additional safeguards or flexibilities that should be considered with respect to the rule.

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Telemedicine Telecommunication Telehealth Medical 59