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Key Facts GPs Should Know About GLP-1 Analogs

Family Medicine Initiative

I therefore reviewed the main research studies and guidelines and tried to summarize them briefly and clearly in this article. Yes, one year after stopping the medication, patients regain ½ – ⅔ of their previous weight loss: What are other clinical benefits? How effective are GLP-1 analogs for weight loss? over 40 months (ARR).

Diabetes 130
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Q&A: Physicians Weigh Improvements in MASLD Treatment Against Gaps in Assessment Strategies

Physician's Weekly

As rates of MASLD, which is linked to obesity and diabetes, rise, new therapies have emerged, but better diagnostic and monitoring strategies are needed. However, as the authors point out, it is likely that combining drugs with differing mechanisms of action will likely lead to greater clinical benefit.

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Health and Mood Benefits of Semaglutide in HF

Physician's Weekly

Source: link.springer.com/article/10.1007/s00392-025-02694-5 The post Health and Mood Benefits of Semaglutide in HF first appeared on Physician's Weekly. Semaglutide therapy in patients with obese heart failure leads to marked weight loss and notable gains in mood, function, and QoL over the course of 1 year.

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Helping Patients Preserve Muscle Mass During Weight Loss

Physician's Weekly

The findings were presented in an abstract at the American Diabetes Association 85th Scientific Sessions. Liver cT1, a biomarker of liver inflammation and fibrosis, decreased slightly (by 1%, or 10 ms), but this change was not clinically significant. These changes were accompanied by more modest declines in muscle mass, including a 3.8%

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Diabetes in Late Life: Nadine Carter, Tamryn Gray, Alex Lee

GeriPal

Summary Transcript Summary Diabetes is common. When I’m on palliative care consults and attending in our hospice unit we have to counsel patients about deprescribing and de-intensifying diabetes medications. And yet we’re also in a different place in diabetes monitoring and management. Goldilocks zone). This is Eric Widera.

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What Pharma Executives Secretly Think About the Future (But Won’t Admit Publicly)

The Medical Futurist

Sometimes, their private visions diverge from their public ones, and this article shares what they won’t admit publicly through four lenses. Some 3D printed drugs made strides some years ago by getting FDA approvals and undergoing clinical trials. One early example is Roche’s acquisition of diabetes management app MySugr.

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Q&A: Prioritizing Early Intervention in Pediatric Obesity

Physician's Weekly

In the article, the researchers note that a minimum of 26 contact hours with the family is required for optimal prevention. The 2023 American Academy of Pediatrics (AAP) Clinical Practice Guidelines has a section that discusses different approaches (eg, virtual visits, including allied providers, thinking about community programs, etc.).