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Rare Diseases: Pathways to accelerating diagnoses 

Myriad Genetics

The NORD report notes: “Genetic testing…is being increasingly utilized to help diagnose rare diseases, the majority of which are genetic in origin. Knowing Which one of those 17 doctors ultimately was able to pull together the pieces of Alex’s health picture and suggest a diagnosis? None of them. It was the AI program ChatGPT.

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Factors Associated with Accumulating Diabetes Complications in a Medicare Advantage Cohort to Inform a Prediction Tool [Diabetes and endocrine disease]

Annals of Family Medicine

Context: Complications contribute to significant type 2 diabetes mellitus (T2DM) morbidity. While preventable, many fail to receive timely treatment in primary care, leading the most vulnerable to accumulate complications. Results: We included 49,843 individuals in model 1. Results: We included 49,843 individuals in model 1.

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Trans Carotid Artery Revascularization

Vascular Physician

The TCAR procedure also utilizes a special tool that reverses the blood flow that usually goes from the aorta to carotid and to the brain. In-hospital complications for either procedure are rare ( The following video is a representation of the procedure: TCAR (Transcarotid Arterial Revascularization) References 1. 2019;58:e638.

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Episode 275: Anti-Racism in Medicine Series – Episode 19 – Reframing the Opioid Epidemic: Anti-Racist Praxis, Racial Health Inequities, and Harm Reduction

The Clinical Problem Solvers

Pearls: In 2020, American Indian and Alaska Native (Indigenous) communities experienced the highest drug overdose mortality rate of any racial or ethnic group, also surpassing rates among the non-Hispanic white population. Epub 2020 Dec 3. Once the need for labor was largely met, anti-Chinese narratives (e.g., link] Castillo, E.

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RCT of Palliative Care for Heart Failure and Lung Disease: David Bekelman and Lyndsay DeGroot

GeriPal

Summary Transcript Summary In a JAMA 2020 systematic review of palliative care for non-cancer serious illness, Kieran Quinn found many positives, as we discussed on our podcast and in our editorial. It used to be a much more complicated model. However, its main predictors are age, comorbidity, and healthcare utilization.

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POLST Evidence and Update: Kelly Vranas, Abby Dotson, Karl Steinberg, and Scott Halpern

GeriPal

As you mentioned, it was published in JAGS in 2020, and we really started from the time of inception of POLST, so in the early 1990s, up until about February 2020 was the date that we cut off. Eric: That’s a complicated form then. I think it was Bob Lee’s 2020 JAGS paper. You write who the surrogate is.

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RCT of PC in ED: Corita Grudzen, Fernanda Bellolio, & Tammie Quest

GeriPal

It was really at the level of the ED across 33 EDs in random order, and then tried to see if we could make a difference in healthcare utilization, primarily the primary outcome was admission to the hospital, acute care admission. Yeah, that’s a more complicated story. But yeah, it’s complicated. Is that right?