Physician's Weekly

JUNE 24, 2025

Recent research showed that ICU statin therapy was associated with significantly lower 28-day all-cause mortality for critically ill patients with sepsis. Statin use is associated with significantly lower 28-day all-cause mortality for critically ill patients with sepsis, according to a study published online in Frontiers in Immunology.

Patient-Centered 52

Patient-Centered Illness Hospital Patients 52

Annals of Family Medicine

NOVEMBER 20, 2024

Methods: We conducted a case-control study in US outpatient settings that enrolled patients aged 18 to 75 years with acute LRTI and controls without respiratory symptoms between 2019 and 2023. All patients underwent PCR testing for 46 bacterial and viral pathogens by the CDC Respiratory Branch Laboratory.

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IT Individual Patients 130

Physician's Weekly

JUNE 14, 2025

Safety was evaluated as a secondary endpoint. The results showed that between August 21, 2019, and June 10, 2022, 1,244 participants were randomized to receive pembrolizumab plus enzalutamide (n=621) or placebo plus enzalutamide (n=623). Prior use of abiraterone was allowed. by blinded independent central review. months (range 6.1–39.8

Individual 52

Individual Patients 52

Plum Health

JULY 6, 2023

In exchange for a monthly, out-of-pocket fee, patients have unrestricted access to their physician and unlimited access to a defined package of services. The Milliman study also highlights the Pareto Principle, which states that 80% of healthcare expenditures come from 20% of patients. As of 2019, 49.6% individual), and 1.4%

Primary Care 52

Primary Care Healthcare Insurance Finance 52

The Clinical Problem Solvers

APRIL 3, 2023

The dehumanization of individuals of color at the margins of society by the healthcare system is not simply a thing of the past, and is certainly a persistent phenomenon. Cindy Gladue, Brian Sinclair, and Joyce Echaquan are three Indigenous individuals who suffered immense harm at the hands of the healthcare system.

Medical 52

Medical Healthcare Individual Community 52

FDA Law Blog

FEBRUARY 28, 2022

Bauer, Senior Regulatory Drug Expert — Our readers probably know that we value and advocate for patient engagement as an essential component in the development of medical products (see our firm’s commitment here ).

Patients 52

Patients Clinic Medical Patient-Centered 52

FDA Law Blog

JUNE 23, 2021

Valentine — For the last 13 years, this blogger has been at the center of what has now been dubbed “patient-focused drug development.” For 6 years, I served as a patient liaison within FDA in what was then called the Office of Special Health Issues. By James E. The practice of medicine was viewed as paternalistic.

Patients 52

Patients Patient-Centered Clinic IT 52

BMJ

JULY 17, 2020

A multilayered view of stigmatizing discourses lays the foundation for eliciting a series of suggestions for quelling stigma, to be implemented at the individual, community, and national levels, as suggested by the WHO. Psychological health during the coronavirus disease 2019 pandemic outbreak. Scholars such as Wen et al.

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Community Individual Physicals Finance 40

FDA Law Blog

OCTOBER 2, 2023

However, the two previous FDA guidance documents, released in May 1998 ( Providing Clinical Evidence of Effectiveness for Human Drug and Biological Products , available here ) and December 2019 ( Demonstrating Substantial Evidence of Effectiveness for Human Drug and Biological Products , available here ), differ from the new guidance.

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IT Clinic Provider Medical 64

The Clinical Problem Solvers

DECEMBER 16, 2020

19:05 Clarifying the “ethics vs science” argument and critiquing research techniques 22:00 Resurgence of race-based speculation in COVID-19-related research 25:57 Implantation of ideas about innate racial inferiority within medicine 28:32 Will removal of race from algorithms potentially harm our patients?

Clinic 52

Clinic Education Clinical Practice Patient-Centered 52

FDA Law Blog

OCTOBER 11, 2022

Additional guidance on confirmatory evidence is sorely needed as the December 2019 draft guidance spends just two of its 18 pages telling us what FDA thinks of such a key piece of statutory language. Conducting a second investigation that tests the same fundamental principles (e.g., a study designed to be externally-controlled).

Clinic 61

Clinic Provider IT Patient-Centered 61

FDA Law Blog

OCTOBER 14, 2024

At the clinics, Defendants offer treatments that consist of extracting fat tissue from patients and, through a multi-step process, turning that tissue into a liquefied mixture of stem cells, other cells and cell debris known as Stromal Vascular Fraction (SVF). 588, 566 (2019)). HCT/Ps that meet the four criteria under 21 CFR 1271.10(a),

Clinic 59

Clinic Patient-Centered Asthma Patients 59

FDA Law Blog

OCTOBER 10, 2022

Javitt — On September 28, 2022, the FDA issued the long anticipated final Clinical Decision Support Software Guidance (CDS Guidance), which replaces the revised draft guidance document from 2019. Criterion 2 : Non-Device CDS software functions display, analyze or print medical information about a patient or other medical information.

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Clinic Medical Provider Patients 52

FDA Law Blog

JUNE 28, 2021

Under current Minnesota law enacted in May 2019, manufacturers that sell, deliver, or distribute into or within Minnesota 2 million or more units of an opiate are required to pay an annual product registration fee of $250,000. One unit equals one tablet, capsule, patch, syringe, milliliter, or gram.” 151.066, Subd.

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Hospital Manufacturing Specialization Medical 52

FDA Law Blog

NOVEMBER 6, 2022

In its petition filed earlier this month, Pfizer challenges HHS’s interpretation of the AKS as “staggeringly overbroad,” contrary to the congressional intent behind the AKS, and a threat to “almost any activity that facilitates patient access to federally funded healthcare.” SCOTUS has until Dec.

Manufacturing 83

Manufacturing Patient-Centered Healthcare Utilities 83

FDA Law Blog

JANUARY 6, 2022

Wasserstein — “EKRA” refers to the Eliminating Kickbacks in Recovery Act, which was part of the Substance Use – Disorder Prevention that Promotes Opioid Recovery and Treatment for Patients and Communities Act of 2018. EKRA is codified at 18 U.S.C. § 220 and was described on HP&M’s blog here. 18 U.S.C. § 24(b) (emphasis added). EKRA Issue.

Lab Testing 52

Lab Testing Referral Individual Patient-Centered 52

FDA Law Blog

MAY 8, 2023

In addition, manufacturers should identify whether the modifications will apply to all devices in the field (referred to as global adaptations) or will be implemented based on a specific clinical site or individual patients” (referred to as local adaptations).

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Manufacturing Provider Medical IT 98

Aspiring Minority Doctor

APRIL 17, 2021

I am 11 hours into my shift and between physical and telemedicine visits, I have seen a total of 46 patients today AND finished all my notes! For the 2019 cycle, I spent a total of $372, and the total spent on the 2020 cycle was $353 (and I forgot to register for SOAP, so did not participate this year). Anyway, back to ERAS.

Medical Student 52

Medical Student IT Telemedicine Medical 52

FDA Law Blog

FEBRUARY 27, 2024

FDA also approved two NDAs on the same first day for micafungin (MYCAMINE)—NDA 021506 for prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation, and NDA 021754 for the treatment of esophageal candidiasis. In that case, the NDA sponsor applied for two PTEs based on these approvals—one for either U.S.

Patients 59

Patients IT Provider Individual 59

FDA Law Blog

JANUARY 6, 2022

Wasserstein — “EKRA” refers to the Eliminating Kickbacks in Recovery Act, which was part of the Substance Use – Disorder Prevention that Promotes Opioid Recovery and Treatment for Patients and Communities Act of 2018. EKRA is codified at 18 U.S.C. § 220 and was described on HP&M’s blog here. 18 U.S.C. § 24(b) (emphasis added). EKRA Issue.

Lab Testing 40

Lab Testing Individual Referral Patient-Centered 40

FDA Law Blog

NOVEMBER 1, 2023

The PR first sets out to establish that it has authority to regulate in vitro diagnostic “test systems” as devices, and not just the system’s individual components, such as reagents, instruments, specimen collection devices, and software.

Manufacturing 81

Manufacturing Hospital Healthcare Medical 81

FDA Law Blog

MAY 17, 2022

FDA approved FIRDAPSE in November 2018, with a period of orphan drug exclusivity, for the treatment of Lambert-Eaton Myasthenic Syndrome (“LEMS”) in adult patients. But in May 2019, FDA approved a second amifampridine drug product, Jacobus Pharmaceutical Company, Inc.’s and more likely 15-20.

IT 40

IT Patients Provider Individual 40

GeriPal

NOVEMBER 9, 2023

The initial RCT published on physician coaching in JAMA in 2019 showing that coaching improves quality of life. ” Eric: It strikes me that there also seems to be a difference between coaching a team, like many of us are familiar with, and this individual coaching, although there may be group coaching as well. We learn in context.

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Annals of Family Medicine

NOVEMBER 20, 2024

Using linked administrative databases, we identified all instances of PIP-AP according to the STOPP-START criteria, which have previously been shown to predict adverse clinical events such as ED visits and hospitalizations.

Patients 130

Patients Provider Individual Hospital 130

The Clinical Problem Solvers

FEBRUARY 8, 2023

Between 2007 – 2019, Black individuals experienced a higher death rate for opioid overdose deaths than any other racial or ethnic group. These narratives have vilified individuals who would benefit from comprehensive, person-centered substance use treatment, rather than incarceration and other adverse harms.

Community 52

Community Patient-Centered Mental Health Board-Certified 52

The Clinical Problem Solvers

APRIL 5, 2022

Our guests remind us to ask our patients about their housing status using non-judgmental and non-stigmatizing language. If we do not know the housing status of our patients, then we do not know one of the most fundamental things that is going to affect their health and wellbeing. 2. Can you refer your patient there? 3.

Community 52

Community Patient-Centered Emergency Room Medical 52

Annals of Family Medicine

NOVEMBER 20, 2024

Some family physicians pursue additional training to become certified as having additional competence in ‘Care of the Elderly’ and/or apply for "focused practice" status to care for older patients. increasingly providing consultations, practicing in long-term care, referring patients aged ?65

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Family Physician Family Families Primary Care 130

The Clinical Problem Solvers

DECEMBER 20, 2021

Fields Guests: Thu Quach, PhD, and Tung Nguyen, MD Time Stamps 00:00 Introduction 04:00 How Dr. Thu Quach’s and Dr. Tung Nguyen’s journeys shape their work 11:40 Policy work as a way of mitigating burnout 12:55 Balancing individual and communal focus (include?) Remember that more deeply understanding your patients can provide meaning!

Community 52

Community Patient-Centered Relationship Healthcare 52

GeriPal

FEBRUARY 27, 2025

We address: Why is caring for patients with this overlap so hard? Sach Kale set up an outpatient clinic focused on substance use disorder for patients with cancer. Who follows the patient once the cancer goes into remission? Why am I having difficulty with this patient? Why am I feeling frustrated with this patient?

Patients 74

Patients Clinic Patient-Centered Illness 74

Physician's Weekly

JUNE 22, 2025

Males had higher levels of urinary mast cell mediators—LTE4, 2,3-BPG, and tryptase—particularly in atopic individuals, compared to females. of patients tested for urinary mast cell mediators were female. Statistical analyses were performed using R. The results showed that 78.8% years), more frequently reported ever smoking (33.5%

Asthma 52

Asthma Utilities Clinic Individual 52

Medical Xpress

DECEMBER 20, 2022

Since December 2019, more than 60 million people have been diagnosed with coronavirus disease 2019 (COVID-19) worldwide, while approximately six million individuals have died as a result of the disease. Hospital treatment was required in about 10%–20% of COVID-19 patients, with this proportion decreasing over time.

Diagnose 73

Diagnose Individual Hospital Patients 73

GeriPal

MARCH 2, 2023

The FDA-approved indications for gabapentin are only for treating patients with partial seizures or postherpetic neuralgia. valproic acid and gabapentin), in nursing homes, particularly patients with Alzheimer’s disease and related dementias. AFP 2019 Gabapentin for chronic neuropathic pain in adults. Tasce: Yes.

Patient-Centered 96

Patient-Centered IT Healthcare Medical 96

GeriPal

MAY 18, 2023

Mike: 2019. Eric: 2019. There are some older adults in whom these are the correct drugs, either because of their particular clinical circumstances or because shared decision making and patient values and preferences. So we want to alert clinicians as well as patients and policy makers to the presence of these drugs.

Medical 97

Medical IT Patients Clinic 97

The Clinical Problem Solvers

MAY 30, 2022

We all must recognize the codification of racism within our institutions and work to unlearn these hierarchies in order to better care for Black and Indigenous patients. She urges us to recognize that maternal mortality changes the life trajectories of individuals and communities. Published January 16, 2019. link] Katy B.

Community 52

Community Patient-Centered Families Family 52

GeriPal

MAY 8, 2025

Summary Transcript CME Summary Weve covered psychedelics on the podcast beforefirst in 2019 with Ira Byock, where we explored their potential role in medicine , and then again in 2023 with Stacy Fischer, Brian Anderson, and Theora Cimino, focusing on the reasons to approach psychedelic use in patients with caution. Ali John 11:34 Yep.

Illness 109

Illness IT Patient-Centered Patients 109

GeriPal

MARCH 9, 2023

Early data on efficacy in patients with anxiety and demoralization are promising. Two of our guests today, Stacy Fischer and Brian Anderson, are involved in large multicenter trials of psychedelics for patients with advanced cancer (Fischer) or life-limiting illness (Anderson). Research is exploding. You’ve been trained?

Patient-Centered 91

Patient-Centered Community IT Medical 91

BMJ

FEBRUARY 8, 2021

Besides the risks to an individual, there are also population-level harms from normalizing certain harmful behaviors (e.g., Increased quality of patient-provider communication, including offering behavioral counseling when needed, may avert unnecessary prescriptions. 2019 Dec;144(6):e20191372. 2019-1372. Pediatrics.

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