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(Published 3/18/19, updated 6/20/25) What Is Physician “Burnout”—and Why It Matters Physician “burnout” is a state of emotional, physical, and mental exhaustion caused by prolonged stress in the medical workplace. So why are physicians experiencing physical and mental collapse from overwork?

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We now have biomarkers that can reasonably approximate the degree of amyloid build-up in the brain with a simple blood test. We have two new FDA-approved medications that reduce that amyloid buildup and modestly slow down the progression of the disease. I just had lab tests done. Nate, welcome back to the GeriPal Podcast.

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William: So ASCO decided to make a high priority this year to redo the guidelines, which were originally released in 2018. And then the duo, physical and cognitive function, those are the seven that… Alex: Oh, that’s a good way of remembering it. Drugs has to do with polypharmacy. I like it, John. William: Yeah.

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