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Vedolizumab Outperformed Infliximab in Real-World Outcomes

Physician's Weekly

The following is a summary of “Treatment sequences, outcomes, healthcare utilization, and costs in patients with inflammatory bowel diseases requiring advanced treatment—real world comparative effectiveness from German claims data,” published in the June 2025 issue of BMC Gastroenterology by Dignass et al.

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Personalized medicine in a community health system: the Endeavor Health experience [Dissemination and implementation research]

Annals of Family Medicine

In 2014, Endeavor Health (formerly NorthShore University HealthSystem) launched the Center for Personalized Medicine to catalyze the delivery of personalized medicine. Population Studied: Ambulatory patients who participated in Endeavor Health Center for Personalized Medicine genomic services.

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A Final LDT Rule in April!? Will FDA be prepared?

FDA Law Blog

14] Thus, while the Third-Party Review Program is not well‑utilized generally, it is not utilized at all by the in vitro diagnostic industry. 2, 2014), [link]. [12] First, FDA notes that the Agency is “currently working to enhance our Third-Party Review Program, which was reauthorized under MDUFA V.” [10] 31, 2023), [link]. [10]

IT 69
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RCT of PC in ED: Corita Grudzen, Fernanda Bellolio, & Tammie Quest

GeriPal

I asked emergency medicine clinicians what they thought when a patient who is seriously ill and DNR comes to the ED, and some responded, (paraphrasing), what are they doing here? Most emergency providers wanted to do the right thing for seriously ill patients, but they didnt have the knowledge, skills, or experience to do it.

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RCT of Default Inpatient PC Consults: Kate Courtright & Scott Halpern

GeriPal

First, in our editorial, we expressed concern about the length of stay metric not being patient centric, though important for health systems focused on cost savings. And, of course, this is what families of patients undergoing palliative care go through. This is 24,000 encounters, over 15,000 patients, 11 hospitals, eight states.

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Private Equity Gobbling Up Hospices plus Hospice and Dementia: Melissa Aldridge, Krista Harrison, & Lauren Hunt

GeriPal

Second, Hospice was originally designed for patients with advanced cancer, but the fastest growing admitting diagnosis is dementia. Krista Harrison found , to her surprise, that caregivers of people with dementia who died rated hospice as well as similar patients without dementia who died on hospice. AlexSmithMD. Transcript.

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Sweet! A Metabolic Disorders focused podcast episode

PEMBlog

She did her MD/PhD at Columbia University, where she investigated the diagnostic utility of exome sequencing for kidney disease. identifying which specific IEM the patient has is part of the later long term evaluation, typically with the help of your friendly geneticist. You can contact her via email at egroopman@childrensnational.org.