Annals of Family Medicine
NOVEMBER 20, 2024
The Osteoarthritis Severity Index (OASI) was developed to inform clinical trajectory of knee OA toward TKA and was previously created and validated in a nationally distributed, general population cohort of EHR data. The first OA diagnosis in record must occur from 2009-2014 and index date is OA diagnosis date.
Louisville Lectures
MAY 25, 2018
After, he reviews elements of the chest physical exam and finally, he reviews the fundamentals of clinical reasoning concerning chest pain. He served as an Assistant Professor at Loyola University while completing his MD at Rush Medical College in Chicago, IL, where he graduated in 2014.
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Adventures of a Sick Doctor
JULY 4, 2024
I opened my diary (an actual physical book, not Outlook) and the silver ribbon is firmly stuck in the week of Wednesday 22nd May. Must have had a rough clinic, I supposed; a family of 4 had gone in before me, and that is never good. I am catching up on various emails and tasks that I have been ignoring for the past few weeks.
FDA Law Blog
JANUARY 12, 2025
Since that time, it was formalized in FDA regulations (21 CFR 314 Subpart H) in 1992, codified in the Food, Drug, & Cosmetic Act by FDAMA (21 USC 356(c)) in 1997, revised by FDASIA in 2012, and described in guidance, most importantly, in the 2014 Expedited Programs for Serious Conditions Drugs and Biologics (2014 Guidance).
FDA Law Blog
NOVEMBER 1, 2023
Regulating LDTs: A Long and Winding Road In what might sound to some like protesting too much, the PR invokes FDA’s longstanding assertion that IVDs “manufactured” by laboratories are medical devices and that clinical laboratories that develop tests are acting as manufacturers. FDA’s position is, however, only one side of the story.
FDA Law Blog
FEBRUARY 29, 2024
A surrogate endpoint is a marker, such as a laboratory measurement, radiographic image, physical sign or other measure that is thought to predict clinical benefit but is not itself a measure of clinical benefit. Drug companies are still required to conduct studies to confirm the anticipated clinical benefit.
Pamela Wible MD
JUNE 20, 2025
(Published 3/18/19, updated 6/20/25) What Is Physician “Burnout”—and Why It Matters Physician “burnout” is a state of emotional, physical, and mental exhaustion caused by prolonged stress in the medical workplace. So why are physicians experiencing physical and mental collapse from overwork?
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