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Development and external validation of the FluScoreVax risk score for influenza that incorporates vaccine status (EAST-PC) [Acute respiratory infections]

Annals of Family Medicine

Objective: To develop and externally validate a simple risk score for influenza diagnosis based only on vaccination history and patient-reported symptoms. Outcome measures: In each study patient-reported symptoms were recorded and PCR used to diagnose influenza. Calibration was assessed by plotting observed versus expected.

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A Reversal on Sequencing? Proposed Legislation Would Allow Patenting of Naturally Occurring Genes

FDA Law Blog

By 2010, about 2000 isolated human genes had been patented in the U.S. In 2010, the Association for Molecular Pathology (AMP), among other organizations, brought suit against Myriad Genetics, challenging the validity of the company’s patents on the BRCA 1/2 genes. HPM is currently representing AMP in unrelated litigation.)

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Going beyond the surface material: A podcast episode on cellulitis

PEMBlog

Anyway, the skin is warm to the touch, it’s uncomfortable, it hurts with movement, and some patients can describe an itchiness or a tight feeling in addition to the pain. So, in general, mild cellulitis has no systemic features in a patient with no significant comorbidities. Vaccinate your children, people. Pediatrics.

IT 59
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Podcast Episode: Febrile Seizures

PEMBlog

Common variants associated with general and MMR vaccine-related febrile seizures. Vaccines don’t cause autism, but they might cause febrile seizures. The absolute risk is small, and genetic susceptibility likely plays a role in seizures after vaccines. You should develop a specific plan for each patient with each patient.

Illness 59