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Validation of an Administrative Knee Osteoarthritis Severity Index in a Veterans Health Affairs Cohort [Big data]

Annals of Family Medicine

The Osteoarthritis Severity Index (OASI) was developed to inform clinical trajectory of knee OA toward TKA and was previously created and validated in a nationally distributed, general population cohort of EHR data. Dataset: VHA-CDW data from 2007-2020.

Diagnosis 130
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Episode 176: Antiracism in Medicine Series – Episode 8 – Towards Justice and Race Conscious Medicine

The Clinical Problem Solvers

The answer to this question may not be easily answered and may not always be found in the clinical setting. However it is important to remember that this political invention DOES affect biology because of the way that it creates social inequity. Pearls: “Genetics is not the end all be all of understanding disease” – Dorothy E.

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Exploring the Use of Intranasal Dexmedetomidine for Anxiolysis and Minimal Sedation

PEMBlog

Dexmedetomidine: a review of clinical applications. 2007 Mar;8(2):115-31. What is Dexmedetomidine? Dexmedetomidine, often known by its brand name Precedex, is a fascinating medication. It’s a highly selective central alpha-2 agonist that’s able to induce a state of sedation that closely mimics natural sleep. Plus, it’s versatile!

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Agitation Podcast Series Episode 5: Management of the child with mental health problems who is boarded in the ED

PEMBlog

Children’s Mental Health Emergency Department Visits: 2007-2016. Characteristics, Clinical Care, and Disposition Barriers for Mental Health Patients Boarding in the Emergency Department. It is also the final episode in a 5 episode series focused on agitation in children and adolescents. Pediatrics. 2020 Jun;145(6):e20191536.

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FDA Cracks Down on ClinicalTrials.gov Reporting Failures

FDA Law Blog

On April 28, FDA issued its first Notice of Noncompliance for failure to submit required clinical trial results information to ClinicalTrials.gov. The ClinicalTrials.gov database is a public database of clinical studies administered by the U.S. Cato & Michelle L. The notice was given to Acceleron Pharma, Inc., 42 U.S.C. §

Clinic 52
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FDA Cracks Down on ClinicalTrials.gov Reporting Failures

FDA Law Blog

Butler — On April 28, FDA issued its first Notice of Noncompliance for failure to submit required clinical trial results information to ClinicalTrials.gov. The ClinicalTrials.gov database is a public database of clinical studies administered by the U.S. Cato & Michelle L. The notice was given to Acceleron Pharma, Inc., 42 U.S.C. §

Clinic 40
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Episode 275: Anti-Racism in Medicine Series – Episode 19 – Reframing the Opioid Epidemic: Anti-Racist Praxis, Racial Health Inequities, and Harm Reduction

The Clinical Problem Solvers

Between 2007 – 2019, Black individuals experienced a higher death rate for opioid overdose deaths than any other racial or ethnic group. Dr. Jordan then questions the utility and continued operation of methadone clinics, especially as the United States largely moves on from the COVID-19 pandemic.