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PEMPix 2024 Online Case #4: Frozen Ever After

PEMBlog

Clinical presentation can include subperiosteal bone hyperplasia, swelling of the overlying soft tissue as well as associated fever and irritability. In addition, congenital syphilis will have other clinical manifestations including cutaneous lesions, jaundice, anemia, and snuffles. It most often affects the mandible and long bones.