article thumbnail

Pain Management Trajectories in Parkinson’s Disease

Physician's Weekly

Opioid initiation continued to rise over time and stayed elevated across all classes in the PD group compared to controls. Investigators concluded that individuals with PD experienced a higher incidence of moderate to severe pain demanding opioid-class analgesics. compared to 31.2% in those without PD.

article thumbnail

FDA’s Draft Guidance on Externally Controlled Trials Answers Some Questions, Leaves Others Unanswered

FDA Law Blog

The Draft Guidance recommends that, where possible, the outcome should be assessed by individuals blinded to treatment status, which may require re-adjudication of externally controlled data. This Draft Guidance focuses on the use of patient-level data from other clinical trials or from RWD sources.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Is Hospice Losing Its Way: A Podcast with Ira Byock and Joseph Shega

GeriPal

I think some individuals thought there was cherry-picking of stories that made it seem like hospice is this bad thing, that it’s taking advantage of vulnerable individuals and it didn’t talk enough about the good things that hospice does. And the big question, is hospice losing its way? Is it you, Ira? Alex: Great choice.

IT 115
article thumbnail

The Future of Geriatrics: A Podcast with Jerry Gurwitz, Ryan Chippendale, and Mike Harper

GeriPal

I’ve seen this question come up a lot since finishing fellowship nearly two decades ago. Historically, answers generally lamented the ever increasing need for geriatrics without a corresponding growth in the number of specialists in the field. Mike, welcome to GeriPal. Mike: Great to be here. Alex: We’ll take any Warriors we can get.

article thumbnail

Episode 240: Anti-Racism in Medicine Series – Episode 17 – ‘Just’ Births: Reproductive Justice & Black/Indigenous Maternal Health Equity

The Clinical Problem Solvers

She urges us to recognize that maternal mortality changes the life trajectories of individuals and communities. Excerpt from Dismantling Racism: A Workbook for Social Change Groups, by Kenneth Jones and Tema Okun, ChangeWork, 2001. This policy reflects a societal belief that humans are not valuable unless they provide a service.

article thumbnail

A Podcast on Inhalant Misuse: From Glue to Galaxy Gas

PEMBlog

Inhalant misuse reported to Americas Poison Centers, 2001-2021. You can either get one little individual canister of nitrous, or a big canister which costs about 120 to 120. Ganetsky M (ed). Updated February 26, 2024. Accessed January 13, 2025. link] Hogge RL, Spiller HA, Kistamgari S, et al. Clin Toxicol (Phila) 2023; 61:453.

article thumbnail

Marijuana: Top Ten Reasons for Descheduling, Rescheduling or Not

FDA Law Blog

Not surprisingly, then-presidential candidate Asa Hutchinson, DEA Administrator from 2001 to 2003, did not sign the letter. The earliest tenured is John Bartels, who served as Administrator from 1973 to 1975. Letter to President Joseph Biden, et al. from Senator Elizabeth Warren, et al. July 6, 2022).

Medical 59